Genomics

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Promega introduces Wizard HMW DNA Extraction Kit ahead of AGBT 2020

Promega, a global biotechnology manufacturer, today launched its new Wizard HMW DNA Extraction Kit for researchers working with large fragments of genomic DNA.

From Promega Corporation 25 Feb 2020

Ancient DNA analysis provides insight into genetic history of Sardinia

A new study of the genetic history of Sardinia, a Mediterranean island off the western coast of Italy, tells how genetic ancestry on the island was relatively stable through the end of the Bronze Age, even as mainland Europe saw new ancestries arrive.

24 Feb 2020

Chromosomal imbalance in cancer cells can either promote or inhibit metastasis

Cancer cells are notorious for their genetic disarray. A tumor cell can contain an abundance of DNA mutations and most have the wrong number of chromosomes.

24 Feb 2020

New way to chart human genome with CRISPR/nanopore sequencing technique

In search of new ways to sequence human genomes and read critical alterations in DNA, researchers at Johns Hopkins Medicine say they have successfully used the gene cutting tool CRISPR to make cuts in DNA around lengthy tumor genes, which can be used to collect sequence information.

24 Feb 2020

IDT's new xGen Prism DNA Library Prep Kit launched

Integrated DNA Technologies, a leading comprehensive genomics solutions provider, has launched the xGen Prism DNA Library Prep Kit, designed to produce high-quality Next Generation Sequencing data from precious but challenging samples, assisting in the early detection of cancer mutations and other applications.

From Integrated DNA Technologies 24 Feb 2020

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive profiling of tumor samples taken from patients with osteosarcoma shows that multiple factors contribute to the traditionally poor responses observed from treatment with immune checkpoint inhibitors, according to new research from The University of Texas MD Anderson Cancer Center.

22 Feb 2020

Isolating Single T-cells of Interest using an Optofluidic Platform

Researchers are in desperate need of single-cell analysis techniques and those that allow the isolation of high-value T-cells for research and development.

From Bruker Cellular Analysis 21 Feb 2020

Researchers discover new mechanism involved in the expression of Down syndrome

Researchers at CHU Sainte-Justine and Université de Montréal have discovered a new mechanism involved in the expression of Down syndrome, one of the main causes of intellectual disability and congenital heart defects in children.

21 Feb 2020

Plant-based relatives of cholesterol could boost gene-infused nanoparticle delivery

Gene-infused nanoparticles used for combating disease work better when they include plant-based relatives of cholesterol because their shape and structure help the genes get where they need to be inside cells.

20 Feb 2020

Random pulsing of gene expression contributes to pattern formation during development

A team of Cambridge scientists working on the intersection between biology and computation has found that random gene activity helps patterns form during development of a model multicellular system.

19 Feb 2020

Marine herbivorous fish could be the new source of protein for humans

A secret to survival amid rising global temperatures could be dwelling in the tidepools of the U.S. West Coast.

19 Feb 2020

Researchers uncover genetic mechanisms that govern brain plasticity

Genetic mechanisms that govern brain plasticity - the brain's ability to change and adapt - have been uncovered by researchers at the University of Birmingham.

18 Feb 2020

UT Southwestern scientists discover potential vulnerabilities in new coronavirus

UT Southwestern Medical Center data scientists analyzing genetic sequences of the COVID-19 coronavirus have identified potential vulnerabilities that could help in vaccine development and further study of the infectious disease now spreading worldwide.

17 Feb 2020

New technique can label diverse molecules in a single tissue sample

A new technique can label diverse molecules and amplify the signal to help researchers spot those that are especially rare. Called SABER (signal amplification by exchange reaction), Peng Yin's lab at Harvard's Wyss Institute first introduced this method last year and since have found ways to apply it to proteins, DNA and RNA.

16 Feb 2020

Novel technique to study gene splicing reveals new insights into the process

Genes are like instructions, but with options for building more than one thing. Daniel Larson, senior investigator at the National Cancer Institute, studies this gene "splicing" process, which happens in normal cells and goes awry in blood cancers like leukemia.

16 Feb 2020

New biological tool can detect and debug faulty genetic circuits

Every cell in our body has a computer-like control system that sends biological signals through thousands of circuits to monitor the cell's needs and regulate its responses.

16 Feb 2020

Research reveals new pathogenic mechanism for influenza NS1 protein

Influenza is a deadly virus, with about 290,000 to 650,000 deaths worldwide each year. When pandemics hit, the toll can soar: The Spanish flu of 1918 caused 40 million to 50 million deaths, the Asian flu of 1957 caused 2 million deaths, and the Hong Kong flu of 1968 caused 1 million deaths.

16 Feb 2020