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A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

Could autophagy enhancement slow aging and combat Alzheimer's?

How cellular cleanup systems could hold the key to slowing aging and halting neurodegeneration.

9 Jan 2025

The X factor: Decoding brain aging differences between men and women

Researchers unveil how biological sex influences brain aging, revealing genetic, hormonal, and molecular mechanisms behind cognitive resilience and decline.

9 Jan 2025

Household dogs found to contribute to the spread of antibiotic-resistant Salmonella

Antibiotic-resistant Salmonella is a serious public health concern that has increased in recent years as the bacteria have developed ways to survive drugs.

9 Jan 2025

New skeletal tissue could revolutionize regenerative medicine and cartilage repair

An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue engineering.

9 Jan 2025

Aircraft noise pollution harms arteries, but heart drugs show promise in animal model research

Alpha- and beta-blockers reduce oxidative stress and inflammation caused by aircraft noise but fail to prevent hypertension, highlighting their potential to protect vascular health in noise-exposed individuals.

9 Jan 2025

Electrical stimulation proven to increase muscle mass and strength

If building strength and muscle mass is part of your New Year's Resolution, you may want to add a new routine to your workout.

9 Jan 2025

Long distances to abortion facilities drive telehealth medication use

The distance between a patient's home and an abortion-services facility where they would seek care significantly influences how they receive birth-control medications, according to a study published Jan. 8 in the American Journal of Public Health.

9 Jan 2025

Lung cancer deaths decrease globally but risk factors still persist

Even though lung and related cancer deaths decreased in the world's 10 most populous countries from 1990 to 2019, these positive statistics do not address trends in mortality linked to tobacco use, air pollution and asbestos exposure.

9 Jan 2025

$20 million grant to explore the role of viruses in human health

For over a decade, scientists have studied the microbiome, the environment of microorganisms that live on and in the body, and how it affects health and disease.

9 Jan 2025

Aston University launches initiative to tackle medication-induced weight gain

Dr. Jo Howe and Professor Ian Maidment from Aston Pharmacy School have won funding for a new project to develop new ways to mitigate weight gain caused by antipsychotic medication.

9 Jan 2025

Can AI chatbots master the science of dietary balance?

Discover how AI chatbots are reshaping weight-loss planning with precision and variety, yet face challenges in balancing macronutrients for optimal health.

9 Jan 2025

Study questions accuracy of genetic test for opioid use disorder

Opioid misuse and specifically opioid use disorder (OUD), continues to represent a significant U.S. public health threat, with more than 6 million Americans aged 12 and older meeting the criteria for OUD in 2022.

9 Jan 2025

Procalcitonin test fails to shorten antibiotic use in hospitalized children

A groundbreaking UK study led by the University of Liverpool has examined whether an additional blood test called procalcitonin (PCT) could safely shorten the time children spend on intravenous (IV) antibiotics in hospitals.

9 Jan 2025

Comorbid atopic diseases affect prognosis of alopecia areata

Asthma, atopic dermatitis or Hashimoto's thyroiditis as concomitant diseases are risk factors for clinical features associated with a poor prognosis in circular hair loss, also known as alopecia areata (AA).

9 Jan 2025

New antibiotic shows promise in fighting tuberculosis

A consortium including scientists from the Tropical Institute at LMU University Hospital has demonstrated the effectiveness of a new antibiotic.

9 Jan 2025

Addressing COPD and metabolic syndrome requires comprehensive research efforts

Additional research addressing the connection between chronic obstructive pulmonary disease (COPD) and metabolic syndrome is needed to improve holistic patient care, according to a new editorial.

9 Jan 2025

Statistical model analyzes the cost-effectiveness of semaglutide for non-diabetic obese individuals

For overweight or obese individuals without diabetes, but with pre-existing cardiovascular disease, semaglutide (Ozempic, Wegovy) is not cost-effective at current pricing, new research shows.

9 Jan 2025

Research from second pig heart transplant provides new directions for xenotransplantation

Continuing significant advancements in the field of xenotransplantation, surgeon-scientists from the University of Maryland School of Medicine provided an extensive analysis on the second patient in the world to receive a genetically-modified pig organ.

9 Jan 2025