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Study reveals route of entry for Semliki Forest virus into the brain

In a recent study, researchers from Uppsala University show that the Semliki Forest virus enters the central nervous system by first entering the cerebrospinal fluid and then binding to a specific cell type before penetrating deeper into the brain.

13 Jan 2025

U.S. dementia cases expected to surge with aging population

A new study shows that the risk of developing dementia anytime after age 55 among Americans is 42%, more than double the risk reported by older studies.

13 Jan 2025

Long reads can revolutionize genetic diagnosis of rare diseases

The cause of rare diseases is increasingly being detected through genome sequencing, which involves reading the entire human DNA by first breaking it into small pieces-short reads.

13 Jan 2025

CeVD-related brain network phenotype can provide insights into cognitive decline trajectory

Researchers have uncovered novel insights into how brain function disruptions related to cerebrovascular disease (CeVD) interact with Alzheimer's disease (AD) pathology to impact neurodegeneration and cognition in older adults.

13 Jan 2025

Genetic discoveries drive new approaches to treating cerebral vascular malformations

Cerebral vascular malformations (CVMs), including cerebral arteriovenous malformations (AVMs) and cavernous malformations (CCMs), have long posed challenges due to their complex origins and severe clinical implications.

13 Jan 2025

NFL players prescribed very few opioids for pain management

Due to the physical contact nature of their occupation, the elite athletes of the National Football League (NFL) often experience pain.

13 Jan 2025

Study reveals how Zika virus hijacks host protein for reproduction

The mosquito-borne Zika virus is known for causing microcephaly, a birth defect in which abnormal brain development results in a smaller-than-expected head.

13 Jan 2025

New research sheds light on changing liver cancer trends

Liver cancer is a leading cause of cancer-related deaths worldwide, with distinct geographic patterns in its incidence.

13 Jan 2025

The impact of extreme weather events on HIV prevention and care

Researchers review the impact of extreme weather events related to climate change on HIV strategies.

13 Jan 2025

Women experience higher waiting-list mortality in lung transplantation

Research highlights gender-based disparities in lung transplantation, showing women face longer wait times yet achieve better post-transplant survival outcomes.

13 Jan 2025

Genetic risk for dementia shapes parenting and family planning choices

Living in a family where there is genetic risk for dementia significantly affects choices about having children and how to parent, finds a new study led by UCL researchers.

13 Jan 2025

Scientists discover why cancer cells die differently after radiotherapy

Scientists at Children's Medical Research Institute have solved a big mystery in cancer research – why cells die in different ways following radiotherapy.

13 Jan 2025

New test could predict lung cancer outcomes using tumor DNA

Scientists from the Francis Crick Institute, UCL, UCLH and Personalis have found that a test to detect circulating tumor DNA can predict lung cancer outcome in a Cancer Research UK-funded study.

13 Jan 2025

Discovery of key protein for burning fat may lead to obesity treatments

Obesity, which affects 650 million people worldwide, influences the development of cardiometabolic diseases and increases the risk of cancer.

13 Jan 2025

Obesity at cancer diagnosis linked to higher risk of death in children

A recent population-based study indicates that among children with cancer, those with obesity at the time of diagnosis may face an elevated risk of dying.

13 Jan 2025

Financial incentives prove successful in supporting pregnant smokers to quit

Rewards and financial incentives are successful methods to help people quit smoking, according to a new Cochrane review co-led by a University of Massachusetts Amherst public health and health policy researcher.

13 Jan 2025

By 2060, 1 million U.S. adults are projected to develop dementia annually

The lifetime risk of dementia is 42%, with significant variations by race and sex, underscoring the importance of public health strategies for prevention.

13 Jan 2025

Gut bacterium associated with reduced dietary sugar intake

This study links Ffar4, gut microbiota, and sugar preference, highlighting potential strategies for managing diabetes and obesity through dietary interventions.

13 Jan 2025

Short-chain fatty acids propionate and butyrate directly modify chromatin to regulate gene expression

Short-chain fatty acids influence gene regulation and chromatin accessibility, highlighting their role in colorectal cancer and normal cellular processes.

13 Jan 2025

Sleep loss triggers intrusive memories by disrupting REM sleep

Sleep deprivation affects the brain's memory control, with REM sleep essential for effective suppression of intrusive memories and cognitive function.

13 Jan 2025