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Targeting miR-4274 and PEX5 can help overcome radioresistance in colorectal cancer

Colorectal cancer (CRC) is a global health concern, and despite advances in radiotherapy, endogenous radioresistance in CRC patients remains a challenge.

9 Jan 2025

Study reveals widespread microplastic contamination in U.S. West Coast fish and shellfish

Researchers measure the levels of anthropogenic particles present in various seafood caught along the West Coat of the United States.

9 Jan 2025

New test predicts lung cancer survival better than current standards

Researchers at the Francis Crick Institute, the UCL Cancer Institute and UCLH have shown that a test called ORACLE can predict lung cancer survival at the point of diagnosis better than currently used clinical risk factors.

9 Jan 2025

Gendered racial microaggressions found to raise blood pressure after childbirth

Gender-based racism through microaggressions may be linked to higher blood pressure postpartum and beyond, according to new research published today in Hypertension, a peer-reviewed journal of the American Heart Association.

9 Jan 2025

Study links fiber consumption to epigenetic changes with anti-cancer effects

Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended amount.

9 Jan 2025

New molecule shows promise in protecting mice from influenza

Researchers at the University of Gothenburg, Sweden, in collaboration with colleagues in China, have discovered an antibody-like molecule that can protect mice from various influenza viruses.

9 Jan 2025

Parvovirus B19 myocarditis cases reported in preschoolers from Northern Greece

Myocarditis is a rare yet serious condition known for the inflammation of the heart muscle, also known as the myocardium. In severe cases of myocarditis, the heart muscle becomes extremely weak and fails to pump blood effectively.

9 Jan 2025

Gut microbes and the body work together to regulate fat metabolism

Beneficial gut microbes and the body work together to fine-tune fat metabolism and cholesterol levels, according to a new preclinical study by investigators from Weill Cornell Medicine and the Boyce Thompson Institute at Cornell University's Ithaca campus.

9 Jan 2025

Maternal medications linked to changes in protein and fat levels in human milk

The impact of maternal antidepressant and anti-inflammatory use on breast milk composition shows reduced protein and fat levels, affecting infant nutrition.

9 Jan 2025

Unraveling the push-pull mechanism of neuron migration

The journey of a thousand miles begins with a single step, but for developing neurons, this first step relies on collaboration from multiple signaling pathways.

9 Jan 2025

Oral medications less effective than insulin for preventing large babies in gestational diabetes study

A study comparing oral glucose-lowering agents to insulin for gestational diabetes found no non-inferiority in preventing large-for-gestational-age infants.

9 Jan 2025

Smoking before age 15 significantly increases risk of chronic lung disease

A study reveals childhood smoking significantly increases COPD risk in adulthood, highlighting the need for targeted prevention strategies for young smokers.

9 Jan 2025

Could camembert cheese hold the key to better memory?

Myristamide enhances cognitive function and BDNF in mice, indicating Camembert cheese's potential in combating cognitive decline and supporting brain health.

9 Jan 2025

Geneoscopy closes $105 M in Series C funding round to power next-generation of gastrointestinal diagnostic tests

Geneoscopy, Inc., a life sciences company focused on developing diagnostic tests for the advancement of gastrointestinal health, today announced the closing of a Series C funding round raising $105 million.

9 Jan 2025

Life expectancy and nursing home admission in people with dementia

The average life expectancy of people diagnosed with dementia ranges from 9 years at age 60 to 4.5 years at age 85 for women and from 6.5 to just over 2 years, respectively, in men, finds a systematic review of the latest evidence in The BMJ today.

9 Jan 2025

Functional characterization of variants improves cancer risk assessment and treatment

Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.

9 Jan 2025

Unraveling the molecular mechanisms of disease-causing mutations

Most mutations which cause disease by swapping one amino acid out for another do so by making the protein less stable, according to a massive study of human protein variants published today in the journal Nature. Unstable proteins are more likely to misfold and degrade, causing them to stop working or accumulate in harmful amounts inside cells.

9 Jan 2025

Monoamine neurotransmitters emerge as architects of brain physiology

A collaborative effort between Mount Sinai and Memorial Sloan Kettering Cancer Center has shed valuable light on how monoamine neurotransmitters such as serotonin, dopamine, and now histamine help regulate brain physiology and behavior through chemical bonding of these monoamines to histone proteins, the core DNA-packaging proteins of our cells.

9 Jan 2025

AI-powered glucose analysis: GPT-4 offers promise with room for refinement

GPT-4 demonstrates its potential in analyzing continuous glucose monitoring data, offering accurate metrics and summaries while highlighting areas for refinement in diabetes care.

8 Jan 2025

Early infections in childhood drive long-term health risks

Early childhood infections significantly increase the risk of severe infections and antibiotic use later in childhood, highlighting the importance of early prevention and monitoring.

8 Jan 2025