Diabetes News and Research

Latest Diabetes News and Research

Semaglutide extended lifespan in older female mice, but that was not the only finding

Late-life semaglutide treatment slowed age-related physiological decline, attenuated multiple molecular hallmarks of aging, and extended median lifespan from 742 to 834 days in aged female mice. The drug reproduced many effects of calorie restriction while providing additional benefits in exploratory behavior, spatial memory, and glucose control, suggesting that some effects extend beyond reduced calorie intake alone.

3 Sep 2026

Coffee, tea and dementia risk: Why the amount you drink could matter

A targeted perspective synthesizes epidemiological and mechanistic evidence examining how caffeine consumption during midlife may influence dementia risk later in life. The authors highlight potential roles for dose, age, CYP1A2 genotype, adenosine signaling and cultural drinking practices, while stressing that current observational evidence cannot establish causality.

3 Sep 2026

Same foods, different timing, very different glucose patterns

In a randomized crossover study of 22 healthy, normal-weight Chinese men, consuming canola oil alone or with spinach before a high-glycemic mashed-potato meal produced flatter post-meal glucose and insulin responses than spinach alone or no preload. The effects were associated with increased GLP-1 signaling and slower gastric emptying, with the findings indicating that the unsaturated oil was the primary driver of the metabolic response.

3 Sep 2026

Study links popular weight-loss drugs to increased male hair loss

Men already at risk genetically for the most common form of hair loss have a 7 percent added risk of losing their hair if they use drugs like Ozempic, Wegovy, and Zepbound for type 2 diabetes and obesity, a new study shows.

3 Sep 2026

Too little or too much testosterone may matter for heart rhythm

A review of clinical trials, observational studies, genetic analyses, and mechanistic research suggests that atrial fibrillation risk may follow a U-shaped relationship with testosterone, increasing at both low and high levels. Evidence on testosterone replacement therapy remains mixed, with researchers calling for prospective studies to determine whether mid-physiological testosterone targets and treatment formulation influence AF risk.

2 Sep 2026

Bright light therapy boosts activity and sleep in older adults

Bright light therapy lamps can improve sleep, activity levels and circadian rhythms of older adults in urban areas who have diminished exposure to natural light, a new study from the University of Surrey reports.

2 Sep 2026

AI learned from cardiologists’ notes, and needed far less labeled ECG data

By teaching an AI system to connect raw heart signals with the clinical insights contained in cardiologists’ reports, researchers tested whether routine ECGs could reveal more with far fewer labeled examples.

2 Sep 2026

Menopause may start changing the gut years before periods stop

A longitudinal study of 964 women found that blood markers of gut epithelial barrier dysfunction and microbial product translocation began to rise around 2 to 2.5 years before the final menstrual period and remained elevated after menopause. The findings suggest that changes in gut barrier integrity may form part of the biological transition through menopause and could help explain links between menopause, inflammation, and later health outcomes.

2 Sep 2026

Why addiction researchers are paying closer attention to GLP-1 drugs

A Journal of Clinical Investigation Viewpoint highlights growing evidence that GLP-1 receptor agonists, particularly semaglutide, may reduce alcohol consumption and some other substance-related outcomes by acting on brain systems involved in reward, motivation, stress, and emotion. However, the authors caution that efficacy for substance use disorders is not yet firmly established and call for further research into optimal dosing, treatment duration, patient selection, mechanisms, and effects across different addictions.

2 Sep 2026

Your weekend meal schedule may matter more than you think

In a prospective analysis of 104,806 adults from the NutriNet-Santé cohort, greater differences in meal timing between weekdays and weekends were associated with higher risks of cardiovascular disease and coronary heart disease in men over a median 8.1 years. The associations were strongest when weekend eating shifted earlier, while delayed weekend eating was linked specifically to coronary heart disease, with no association detected for cerebrovascular disease.

2 Sep 2026

Generative AI helps scientists design entirely new RNA transporters

Researchers at Helmholtz Munich and TUM have developed Synthetic Transfer Vehicles (STVs), an entirely new class of RNA transporters.

2 Sep 2026

Bridging science and family story to understand schizophrenia origins

Twin studies have placed the heritability of schizophrenia at roughly eighty percent for decades. Concordance between identical twins, who share the entire genome, does not reach fifty percent. Both figures are well established, and they do not fit together comfortably.

2 Sep 2026

Bacterial protein fragment corisin found to drive pulmonary fibrosis

A bacterial protein fragment called corisin drives the process of pulmonary fibrosis by infiltrating and disrupting the cell's quality-control system, researchers at the University of Illinois Urbana-Champaign and Mie University in Japan found in a new study.

2 Sep 2026

Digital health coaching moves into routine care for gestational diabetes

Researchers at University College Dublin (UCD) published the full study protocol for Bump2Baby & Me+ (B2B&Me+) today.

2 Sep 2026

ECG-CLIP improves heart disease detection using less labeled data

Clinicians often use a medical test called a 12-lead electrocardiogram (ECG) to diagnose heart problems, which uses electrodes placed on the chest and limbs to record the heart's electrical activity.

1 Sep 2026

Certain diabetes patients face higher ketoacidosis risk with SGLT2 drugs

Patients with type 2 diabetes who have high blood glucose levels, low body weight, or a history of ketoacidosis are at increased risk of developing this serious condition when treated with so-called SGLT2 inhibitors.

1 Sep 2026

Flavorings, colors and sweeteners emerge as UPF markers linked to depression risk

A prospective UK Biobank study of 171,818 adults found that greater estimated exposure to foods containing flavorings, coloring agents, and sweeteners was dose-dependently associated with a higher risk of incident depression over 10.7 years. The findings suggest that specific markers, rather than ultra-processed foods uniformly, may help explain associations between UPF consumption and depression risk.

1 Sep 2026

Researchers identify a previously unknown mechanism that can drive cancer cachexia

Researchers at Helmholtz Munich, the Heidelberg Faculty of Medicine at Heidelberg University, the German Center for Diabetes Research (DZD) and the Technical University of Munich (TUM), have identified a previously unknown mechanism that can drive cancer cachexia – a wasting process in the body that primarily affects muscle and fat tissue.

1 Sep 2026

Blocking a key protein protects against metabolic liver damage

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some fraction of those livers develop scarring, become inflamed, and eventually fail. University of Utah researchers have identified a protein, EFHD1, that appears to drive that transition by triggering an out-of-place antiviral immune response.

1 Sep 2026