Epigenetics News and Research

Latest Epigenetics News and Research

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Global disparities in Alzheimer's and dementia burden linked to sociodemographic factors

An analysis of the global burden and temporal trends of Alzheimer's disease and other dementias (ADODs) reveals significant cross-country inequalities associated with a series of sociodemographic development-related risk factors, such as education, income, fertility, and health expenditure. The new study in the American Journal of Preventive Medicine, published by Elsevier, calls for the development of targeted prevention and control strategies in different countries.

11 Mar 2025

Understanding the role of LSD1 in cellular processes and disease

A new review highlights the pivotal role of LSD1 (lysine-specific demethylase 1) in regulating critical cellular processes and its implications for human diseases.

8 Mar 2025

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Lung cancer remains one of the leading causes of cancer-related mortality, with lung adenocarcinoma (LUAD) and lung squamous cell carcinoma (LUSC) representing the most prevalent subtypes of non-small cell lung cancer (NSCLC).

8 Mar 2025

Circular RNA plays key role in cancer biology and therapy

A new review article highlights the transformative role of circular RNA (circRNA) in cancer, revealing its potential as both a key player in tumor biology and a promising avenue for future therapies.

8 Mar 2025

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, recurrence, and drug resistance.

8 Mar 2025

EZH2 inhibition offers hope for fighting treatment-resistant cancers

The critical role of EZH2, an essential epigenetic regulator, in cancer progression and treatment is underscored in this new review article published in Genes & Diseases.

8 Mar 2025

DEVOTION focuses on understanding birth trauma and optimizing birth experience

As we mark International Women's Day tomorrow on March 8, the story of the COST Action on Perinatal Mental Health and Birth-Related Trauma: Maximizing best practice and optimal outcomes (DEVoTION) is a powerful example of how collaborative research can both advance women's health and support the next generation of women researchers.

7 Mar 2025

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

This newly published analysis in Genes & Diseases sheds light on the crucial role of mechanosensitive adhesion G protein-coupled receptors (aGPCRs) in regulating biological processes and their implications in various diseases.

5 Mar 2025

Study sheds light on the role of fibro-adipogenic progenitors in muscle regeneration and degeneration

A recent study has shed new light on the role of fibro-adipogenic progenitors (FAPs) in muscle regeneration, fibrosis, and degeneration.

5 Mar 2025

Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

A new review published in Genes & Diseases highlights macrophage-targeted therapy as a promising frontier in cardiac regeneration and myocardial repair.

5 Mar 2025

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

A new review article published in Genes & Diseases explores the intricate relationship between non-coding RNAs and oxidative stress in cancer progression shedding new light on the mechanisms that drive tumor development.

5 Mar 2025

Study links environmental chemical exposures to faster biological aging

A new research paper was published in Aging (Aging-US) on February 11, 2025, Volume 17, Issue 2, titled "Exposome-wide association study of environmental chemical exposures and epigenetic aging in the national health and nutrition examination survey."

5 Mar 2025

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

This recently published exploration into the subventricular zone (SVZ) highlights its critical role in neural regeneration, neurodegenerative diseases, and glioblastoma multiforme (GBM).

5 Mar 2025

Targeting mitochondrial DNA integrity for cardiac protection after injury

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.

4 Mar 2025

TFE3 activation shows promise for counteracting Parkinson's disease pathology

This recent study highlights the neuroprotective potential of TFE3, a transcription factor that plays a pivotal role in counteracting key pathological mechanisms associated with Parkinson's disease (PD).

2 Mar 2025

Exploring the role of SNPs in early diagnosis of coronary microvascular dysfunction

A new review highlights the potential role of single nucleotide polymorphisms (SNPs) in improving the early diagnosis and targeted intervention of coronary microvascular dysfunction (CMD)—a condition linked to myocardial ischemia despite the absence of major artery blockages.

26 Feb 2025

Epigenetics News and Research

Latest Epigenetics News and Research

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

Deciphering the tumor-immune interplay in endometrial carcinoma

Study reveals TCM-Based strategies for ferroptosis modulation

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

Global disparities in Alzheimer's and dementia burden linked to sociodemographic factors

Understanding the role of LSD1 in cellular processes and disease

Unraveling the genetic differences between LUAD and LUSC in lung cancer

Circular RNA plays key role in cancer biology and therapy

Ubiquitination plays a key role in cancer stem cell function and treatment resistance

EZH2 inhibition offers hope for fighting treatment-resistant cancers

DEVOTION focuses on understanding birth trauma and optimizing birth experience

Insights into mechanosensitive aGPCRs and their role in biological processes and disease

Study sheds light on the role of fibro-adipogenic progenitors in muscle regeneration and degeneration

Macrophage-targeted therapy could enhance cardiac regeneration and myocardial repair

Exploring the relationship between non-coding RNAs and oxidative stress in cancer progression

Study links environmental chemical exposures to faster biological aging

Exploring the role of subventricular zone in neural regeneration, neurodegenerative diseases

Targeting mitochondrial DNA integrity for cardiac protection after injury

TFE3 activation shows promise for counteracting Parkinson's disease pathology

Exploring the role of SNPs in early diagnosis of coronary microvascular dysfunction

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Epigenetics News and Research

Latest Epigenetics News and Research

eBook: A guide to RNA sequencing eBook

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh

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