Epigenetics News and Research

Latest Epigenetics News and Research

Macrophage memory following COVID infection provides cross-virus protection

More than 200 viruses can infect and cause disease in humans; most of us will be infected by several over the course of a lifetime.

30 Sep 2024

AI-powered blood test promises early detection of ovarian cancer

A blood test that uses artificial intelligence (AI) to detect cancer-related genetic changes and protein biomarkers could help screen women for early signs of ovarian cancer, according to a study by researchers at the Johns Hopkins Kimmel Cancer Center in collaboration with several other institutions in the United States and Europe.

30 Sep 2024

Groundbreaking project seeks to illuminate the complexities of Parkinson's

Launching today, Landmark is a groundbreaking three-year research programme that aims to understand Parkinson’s in unprecedented detail. The project brings together Parkinson’s UK, Imperial College London, GSK, Novartis, Roche and UCB for the first time, and has been made possible by a founding gift of £4 million from the Gatsby charitable foundation.

24 Sep 2024

Hypoxia's hidden role in boosting anti-cancer immunity

In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.

19 Sep 2024

New biomarkers offer hope for early detection and prevention of Alzheimer's

The failure to diagnose Alzheimer's disease, the most common form of dementia in the elderly, at an early stage of molecular pathology is considered a major reason why treatments fail in clinical trials. Previous research to molecularly diagnose Alzheimer's disease yielded "A/T/N" central biomarkers based on the measurements of proteins, β-amyloid ("A") and tau ("T"), and "N" encompassing neurodegeneration. A/T/N can be measured in brain tissue, by in vivo brain imaging techniques, and by analysis of cerebrospinal fluid and plasma.

18 Sep 2024

Discovery of 5-formylcytosine as an activating epigenetic switch

The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating epigenetic switch that kick-starts genes in early embryonic development.

18 Sep 2024

INTEGRA Biosciences’ pipettes pave the way for epigenetics testing

Genknowme, a start-up specializing in epigenetics research, has integrated multichannel pipettes from INTEGRA Biosciences into its liquid handling workflows. These liquid handling solutions will enable the lab to provide fast epigenetic assessments that will support healthcare professionals in suggesting lifestyle changes to improve their patients’ quality of life.

From INTEGRA Biosciences 17 Sep 2024

ESMO Congress 2024 to unveil future-focused cancer treatments

The ESMO Congress 2024 will hold a press conference to introduce and discuss the "Eyes to the Future" Presidential Symposium 3, that will be presenting prominent approaches that have the potential to become increasingly effective and influential components of cancer treatment in the (near) future.

16 Sep 2024

AI reveals new drug targets for cancers with limited treatment options

Researchers at Weill Cornell Medicine have used artificial intelligence to identify drug targets based on mapping regulatory networks in patient tumors.

5 Sep 2024

Unraveling psychiatric disorders with cutting-edge epigenetic tools

The "Innovators & Ideas: Rising Star" section of Genomic Psychiatry features an illuminating "Genomic Press Interview" with Dr. Pierre-Eric Lutz, a rising star in the field of neuro-epigenetics.

5 Sep 2024

Research highlights potential of blood epigenetics for dementia risk assessment

New research suggests that epigenetic markers in the blood could be useful for understanding dementia risk.

28 Aug 2024

CDCA7 identified as key player in hemimethylation sensing

DNA methylation is a process in which a methyl group is attached to the cytosine base of the DNA molecule, and a major way that DNA is epigenetically marked.

28 Aug 2024

Austocystin D's anticancer efficacy linked to CYP2J2 enzyme activity

Austocystin D, a natural compound produced by fungi, has been recognized for its cytotoxic effects and anticancer activity in various cell types. It exhibits potent activity even in cells that express proteins associated with multidrug resistance, attracting significant global research interest.

27 Aug 2024

Grandparental education predicts grandchildren's biological age

Eating well, exercising and attending regular doctor appointments can support a long healthy life, but a new study identified one possible factor beyond our control: whether you had a grandparent who went to college. The study, from researchers at Drexel University and colleagues from the University of California and the University of North Carolina, was recently published in the journal Social Science and Medicine.

27 Aug 2024

Immune cells' two-pronged approach to maintaining acetyl-CoA reserves

Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.

23 Aug 2024

Study sheds light on the dual nature of cellular senescence

Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.

22 Aug 2024

New insights into macrophages' role in MASH and liver fibrosis

Formerly known as nonalcoholic steatohepatitis, metabolic dysfunction-associated steatohepatitis (MASH) is an inflammatory disease characterized by liver scarring or fibrosis that progressively impairs liver function.

22 Aug 2024

New discovery reveals how DNA regulates inheritance of disease mutations

University of Queensland researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited.

21 Aug 2024

Breakthrough research unveils retroelement-based aging biomarkers

Researchers at Weill Cornell Medicine and the epigenetics company TruDiagnostic have uncovered DNA markers associated with retroelements, remnants of ancient viral genetic material, in our genes that act as highly accurate epigenetic clocks predicting chronological age.

19 Aug 2024

New Springer textbook provides a comprehensive overview of aging science

A new textbook provides an overview on the present understanding of aging - from the basic biology of aging to age-related diseases and to the role of lifestyle and the environment.

19 Aug 2024