Life Science White Papers

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Life Science White Papers are in-depth articles aimed to educate and inform site visitors interested in life science research. Some of these papers are derived from sources where we have existing commercial relationships. Such articles are clearly labelled as sponsored content and are only accepted when the content is deemed to add value to the core editorial ethos of News Medical.

Growth Factor Receptor Signaling for Cancer Research

Growth Factor Receptor Signaling for Cancer Research

Growth factor receptor signaling for cancer research focuses on the dysfunctional regulation of cancer cells that causes the runaway growth of the cells.

From Tocris Bioscience 6 Aug 2019

Modulation and Functions of MAP Kinase Pathways

Modulation and Functions of MAP Kinase Pathways

Modulation and functions of MAP kinase pathways are crucial to produce appropriate intracellular responses from extracellular signals

From Tocris Bioscience 2 Aug 2019

A Review of Epigenetics

A Review of Epigenetics

Separate from the underlying DNA, epigenetics formed by the changes in chromatin structure which alter the accessibility of DNA to transcription machinery.

From Tocris Bioscience 2 Aug 2019

Epigenetic Drug Targets of Rheumatoid Arthritis

Epigenetic Drug Targets of Rheumatoid Arthritis

Epigenetic drug targets of rheumatoid arthritis target the breakdown of the immune tolerance that is thought to cause the symptoms.

From Tocris Bioscience 2 Aug 2019

Metabolism and Gut Hormones

Metabolism and Gut Hormones

The gut is the largest endocrine organ in the body with a dramatic effect on metabolism, gut hormones are produced by the pancreas & gastrointestinal tract.

From Tocris Bioscience 2 Aug 2019

GPCR Regulation of the Vascular System and Dysfunction

GPCR Regulation of the Vascular System and Dysfunction

Despite widespread use of drugs targeting GPCR regulation of the vascular system, cardiovascular disease remains the cause of 30% of deaths globally.

From Tocris Bioscience 2 Aug 2019

How Can NMR Help To Identify Novel Cervical Cancer Treatments?

How Can NMR Help To Identify Novel Cervical Cancer Treatments?

This article describes a study in which NMR analysis of fig latex showed potential as a treatment for cervical cancer.

From Bruker BioSpin - NMR, EPR and Imaging 30 Jul 2019

Therapeutic Antibody Quantification in Serum Samples Using ELISA Assay Kits

Therapeutic Antibody Quantification in Serum Samples Using ELISA Assay Kits

The booming biologic drug market driven by mAb success necessitates standard high-throughput ELISA assay kits for therapeutic antibody quantification.

From ACROBiosystems 29 Jul 2019

Studying the Evolution of Protein-Protein Interactions with NMR

Studying the Evolution of Protein-Protein Interactions with NMR

This article describes how NMR can be used in the analysis of protein-protein interactions.

From Bruker BioSpin - NMR, EPR and Imaging 24 Jul 2019

An Introduction to P2X and P2Y Receptors

An Introduction to P2X and P2Y Receptors

The P2X and P2Y receptors for extracellular nucleotides participate in regulation of many physiological processes.

From Tocris Bioscience 23 Jul 2019

A Review of Histamine Receptors

A Review of Histamine Receptors

As an aminergic neurotransmitter, histamine and histamine receptors play a key role in many pathophysiological processes.

From Tocris Bioscience 23 Jul 2019

Appetite Modulation Peptides

Appetite Modulation Peptides

The expression of appetite is commonly thought to be chemically coded through the excitation and modulation of peptides.

From Tocris Bioscience 23 Jul 2019

Drug Targets and Neurobiology of Schizophrenia

Drug Targets and Neurobiology of Schizophrenia

There are many hypotheses regarding the neurobiology of schizophrenia, and many drug targets have been researched and tested.

From Tocris Bioscience 23 Jul 2019

Pharmacology of Allosteric G Protein-Coupled Receptors

Pharmacology of Allosteric G Protein-Coupled Receptors

The allosteric nature of G protein-coupled receptors transduce signals from spatially distinct binding sites of a the protein.

From Tocris Bioscience 23 Jul 2019

Modulating Peripheral Sensitization Through Excitability of Sensory Neurons

Modulating Peripheral Sensitization Through Excitability of Sensory Neurons

Modulating peripheral sensitization involves increasing or reducing the threshold of excitability of sensory neurons to stimuli.

From Tocris Bioscience 19 Jul 2019

Photolysis: Photolabile Precursors of Ligands

Photolysis: Photolabile Precursors of Ligands

Photolabile precursors of relevant ligands (caged compounds) are needed in the experimental tool photolysis.

From Tocris Bioscience 19 Jul 2019

An Introduction to Neurotransmission Research

An Introduction to Neurotransmission Research

Synaptic or neurotransmission research refers to the study of signals between neurons, and the propagation of action potentials to disperse information.

From Tocris Bioscience 19 Jul 2019

An Introduction to Huntington's Disease

An Introduction to Huntington's Disease

Huntington's Disease is an autosomal dominant neurodegenerative disease characterized by mental decline and motor dysfunction.

From Tocris Bioscience 19 Jul 2019

Neurodegeneration: Progressive Neuron Death

Neurodegeneration: Progressive Neuron Death

Progressive neuron death, otherwise known as neurodegeneration, commonly leads to loss of function and structure in the brain.

From Tocris Bioscience 19 Jul 2019

Immune Programming in Plants Identified by EPR

Immune Programming in Plants Identified by EPR

The way that plants defend themselves against pathogenic organisms was recently investigated with electron paramagnetic resonance (EPR).

From Bruker BioSpin - NMR, EPR and Imaging 16 Jul 2019

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