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Age and sex shape Alzheimer’s blood biomarkers, study finds

ESTHER study found that non-modifiable factors like age, sex, and APOE ε4 status significantly influence blood biomarker levels linked to Alzheimer’s disease. GFAP and NfL levels, in particular, showed strong age- and sex-related patterns, with GFAP levels rising faster in women.

22 Apr 2025

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity-two issues that commonly co-occur with alcohol use disorder (AUD).

22 Apr 2025

Obesity alters the rhythm of liver’s starvation response

Researchers led by Keigo Morita and Shinya Kuroda of the University of Tokyo have revealed a temporal disruption in the metabolism of obese mice when adapting to starvation despite no significant structural disruptions in the molecular network.

22 Apr 2025

AGA announces $2.4 million in research funding for 74 recipients

The American Gastroenterological Association (AGA) is proud to announce the selection of 74 recipients to receive $2.4 million in research funding through the annual AGA Research Foundation Awards Program.

22 Apr 2025

Temporary anxiety disrupts spatial learning and threat recognition

A brief episode of anxiety may have a bigger influence on a person's ability to learn what is safe and what is not.

22 Apr 2025

Mayo Clinic study reveals brain cell deficit behind Tourette syndrome

A new Mayo Clinic study finds that people with Tourette syndrome have about half as many of a specific type of brain cell that helps calm overactive movement signals as people without the condition.

22 Apr 2025

Targeting zombie cells could revolutionize chronic back pain treatment

In a preclinical study led by McGill University researchers, two drugs targeting "zombie cells" have been shown to treat the underlying cause of chronic low back pain. The condition affects millions of people worldwide.

22 Apr 2025

China's malaria-free status offers key lessons for global efforts

China's success in achieving malaria-free status in 2021 offers crucial lessons for the global malaria fight, say experts in a special collection of articles published by The BMJ today.

22 Apr 2025

New $15 million study aims to understand cardiovascular and kidney disease risk factors in women

Research teams from Augusta University, Massachusetts General Hospital and The Ohio State University will lead a $15 million project dedicated to studying the various ways that risk factors for cardiovascular and kidney diseases impact women.

22 Apr 2025

Study shows how alcohol combined with burn trauma throws the intestinal microbiome into chaos

What happens in your gut after a night of heavy drinking and a severe burn injury? According to a new study, it might involve more than just pain and discomfort.

22 Apr 2025

High-risk adults often do not receive timely flu treatment, study finds

A multi-state study reveals that many high-risk adults diagnosed with influenza (flu) in emergency departments and urgent care centers are not receiving timely antiviral treatment.

22 Apr 2025

New subtype of Castleman disease identified to improve diagnosis and treatment

A newly identified subtype of Castleman disease will help diagnose and properly treat thousands of patients who have been caught between existing classification systems, marking the first major discovery of its kind in 45 years.

22 Apr 2025

Longer sleep and earlier bedtimes linked to better brain function in adolescents

Adolescents who sleep for longer – and from an earlier bedtime – than their peers tend to have improved brain function and perform better at cognitive tests, researchers from the UK and China have shown.

22 Apr 2025

New insights show why dopamine detox trend is overly simplistic

Dopamine is the brain's motivational spark, driving us to chase what feels good, say scrolling another reel on social media, and steer clear of what doesn't, like touching a hot stove.

22 Apr 2025

Research reveals significant increase in ME/CFS cases across England

There are almost two-thirds more people living with ME/CFS in England than previously thought, a study says.

22 Apr 2025

A simple nudge leads to more statin prescriptions and better health

With a simple click, doctors can potentially save lives and reduce heart attack and stroke risks for thousands of patients by helping them have their statins on hand.

22 Apr 2025

New study sheds light on 3D gene hubs driving brain cancer

The way DNA folds inside the nucleus of brain cells may hold the key to understanding a devastating form of brain cancer called glioblastoma, suggests a new preclinical study from Weill Cornell Medicine researchers.

22 Apr 2025

Liquid biopsy offers new hope for early cancer detection

Cancer is one of the leading causes of death globally, with nearly 20 million new cases and 9.7 million deaths in 2022.

22 Apr 2025

Mount Sinai researchers enhance AI tool to better detect heart disease risk

Mount Sinai researchers studying a type of heart disease known as hypertrophic cardiomyopathy (HCM) have calibrated an artificial intelligence (AI) algorithm to quickly and more specifically identify patients with the condition and flag them as high risk for greater attention during doctor's appointments.

22 Apr 2025

Dr. Jeremie Poschmann's data-driven approach to immunology and translational science

In a wide-ranging Genomic Press Interview, Dr. Jeremie Poschmann of INSERM and Université de Nantes shares the story behind his bold, data-centric approach to immunology and translational science.

22 Apr 2025