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Genetic risk factor linked to increased susceptibility to SARS-CoV-2 infection

Researchers have identified a novel genetic risk factor for SARS-CoV-2 infection, providing new insights into the virus' ability to invade human cells. SARS-CoV-2 is the virus that spreads COVID-19.

15 Jan 2025

Pheno Therapeutics granted clinical trial authorization for lead multiple sclerosis therapeutic candidate PTD802

Pheno Therapeutics Limited., a biotechnology company focused on the discovery and development of small molecule therapeutics for the treatment of neurological diseases, announced today it has received clinical trial authorization (CTA) from the UK’s MHRA (Medicines and Healthcare products Regulatory Agency) for its lead candidate, PTD802.

From Pheno Therapeutics 15 Jan 2025

IVF and ICSI pregnancies show higher exposure to teratogenic medicines

A new Australian study has revealed a potential reason why some pregnancies achieved through assisted reproductive technology (ART) may result in birth defects in comparison to naturally conceived pregnancies.

15 Jan 2025

GroceryDB helps shoppers spot ultra-processed foods

This open-source database utilizes machine learning to assess food processing, promoting nutrition security and informed consumer choices in the grocery market.

15 Jan 2025

Terumo Blood and Cell Technologies and FUJIFILM Irvine Scientific collaborate to accelerate T cell expansion for cell therapy developers

Terumo Blood and Cell Technologies (Terumo BCT) and FUJIFILM Irvine Scientific have announced a strategic collaboration to help accelerate T cell expansion using Fujifilm's PRIME-XV® T Cell Expansion Media on Terumo BCT’s Quantum Flex™ Cell Expansion System.

From FUJIFILM Irvine Scientific 15 Jan 2025

Study reveals how bile acids impact immunotherapy in liver cancer

Immunotherapy is a modern approach to cancer treatment that uses a patient's own immune system to help fight tumors.

15 Jan 2025

CAR-NK cells offer safer, more accessible treatment for lymphoma

A new type of cell-based immunotherapy shows promise for B-cell lymphomas and - due to innovations in manufacturing - could make future cellular immunotherapies less expensive and more accessible to patients.

15 Jan 2025

Ultrasensitive ctDNA detection improves risk prediction in early-stage lung cancer

Ultrasensitive ctDNA detection with NeXT Personal shows 81% sensitivity in early-stage lung adenocarcinoma, improving prognostic accuracy and therapy guidance.

15 Jan 2025

New gene-editing treatment extends lifespan in mice with prion disease

Researchers at the Broad Institute of MIT and Harvard have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition.

15 Jan 2025

Racism in obstetric care linked to higher blood pressure in mothers

Mothers of color who faced racism or microaggressions during obstetric care had higher blood pressure after delivering their babies compared to people of color who did not report racism during their care, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

15 Jan 2025

Midwives blame California rules for hampering birth centers amid maternity care crisis

Jessie Mazar squeezed the grab handle in her husband's pickup and groaned as contractions struck her during the 90-minute drive from her home in rural northeastern California to the closest hospital with a maternity unit.

15 Jan 2025

I’m moving forward and facing the uncertainty of aging

It takes a lot of courage to grow old. I've come to appreciate this after conversations with hundreds of older adults over the past eight years for nearly 200 "Navigating Aging" columns.

15 Jan 2025

Overcoming limitations of traditional CVD drugs

Announcing a new publication for Acta Materia Medica journal. Cardiovascular diseases (CVDs) pose a significant threat to human health due to the high mortality and morbidity rates. Traditional drugs often have limited efficacy due to inherent constraints, such as low bioavailability and notable side effects.

15 Jan 2025

The role of inflammation in the pathogenesis of heart failure

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiovascular disease remains a leading cause of death and disability worldwide. Heart failure (HF) is the end stage of various cardiovascular diseases. Despite recent advancements in understanding of HF pathogenesis and treatment, the prognosis of patients with HF remains poor.

15 Jan 2025

Researchers uncover new mutation mechanism driving cancer progression

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a significant impact on young people and their families as treatment can require surgery or amputation.

15 Jan 2025

Pharmacokinetics of berberine and astragaloside IV in normal and diabetic rats

Announcing a new publication for Acta Materia Medica journal. The UPLC-QqQ-MS/MS method was established, validated, and used for the simultaneous detection of berberine (BBR), astragaloside IV (AST), and the main metabolites to demonstrate the comparative pharmacokinetics of BBR and AST in normal and T2DM rats.

15 Jan 2025

Study finds no increased glioma risk with hormone therapy use

It's not easy being a woman. Just look at the statistics. Women are more likely to have such debilitating conditions as osteoporosis, migraines, Alzheimer disease, depression, multiple sclerosis, and brain tumors. Sex hormones are often blamed. However, a new study suggests no link between hormone therapy (HT) and common brain tumors known as gliomas. Results of the study are published online today in Menopause, the journal of The Menopause Society.

15 Jan 2025

Machine learning identifies women at risk of severe cognitive decline during menopause

Artificial intelligence (AI) is positioned to make a major impact on almost every industry, including healthcare. A new study suggests that machine learning models can more quickly and affordably identify women with severe subjective cognitive decline during the menopause transition, effectively opening the door to better management of cognitive health. Results of the study are published online today in Menopause, the journal of The Menopause Society.

15 Jan 2025

Study unravels the links between obesity and cancer

Obesity, recognized as a complex and growing health issue, is associated with an increased risk of various cancers. A comprehensive review provides insights into the mechanisms linking obesity to cancer risk and discusses potential clinical implications.

15 Jan 2025

Uncovering the neurobiological mechanisms of delta opioid receptor agonists

The global burden of anxiety- and depression-related disorders is on the rise. While multiple drugs have been developed to treat these conditions, current medications have several limitations, including slow action and adverse effects with long-term use. This underscores the urgent need for novel, rapidly-acting therapeutic agents with minimal side effects.

15 Jan 2025