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Revolutionary strategy offers hope for type 1 diabetes treatment

Regenerative medicine holds the extraordinary promise that future patients in need of new cells, tissues or organs will no longer have to rely on donors. Organ shortages and cell type mismatches will become past problems, replaced by safe, on-demand options for anyone who needs a transplant.

25 Nov 2024

New insights into leptin's role in hypothalamic neural circuit development

Researchers from the Vanderbilt University School of Medicine Basic Sciences have uncovered the first example of activity-dependent development of hypothalamic neural circuitry.

25 Nov 2024

How neural and hormonal gut-brain communication shapes metabolism and health

Interoception research reveals how gut-brain communication via neural, hormonal, and microbial pathways regulates metabolism, hunger, and overall health, offering insights for therapeutic innovations.

25 Nov 2024

Addressing the challenges of cognitive impairment detection in primary care

Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. This special report summarizes key points and gaps in knowledge about methods for detecting cognitive impairment in primary care clinics.

25 Nov 2024

Peer support program shows promise for cancer patients in Vietnam

Having cancer can be one of the most physically and emotionally draining experiences of a person's life, but navigating this disease without adequate support or resources makes this journey even more burdensome.

25 Nov 2024

New therapy from UI Health becomes the first FDA-approved treatment for brittle type 1 diabetes

A new therapy for brittle type 1 diabetes, the only treatment currently approved by the U.S. Food and Drug Administration, is available exclusively at UI Health in Chicago.

25 Nov 2024

New discovery reveals dual binding in bitter taste receptors

"Tasting Upside-Down - An Unusual Sensing Mechanism was Found in Human Bitter Sensing" A new study revealed that some bitter molecules target their sensor through binding simultaneously at two distinct locations, one outside the cell, and the other inside it.

25 Nov 2024

New AI model tailors phage treatment for resistant bacterial infections

With the rapid development of antibiotics in the 1930s, phage therapy – using viruses known as bacteriophages or phages to tackle bacterial infections – fell into oblivion.

25 Nov 2024

Study links mother's emotional speech to infant oxytocin levels

Infants whose mothers regularly use language to describe what their child is thinking or feeling, have higher levels of the hormone oxytocin, finds a new study led by UCL researchers.

25 Nov 2024

New brain biomarker could enable early diagnosis of psychosis

The current standard of care for psychosis is a diagnostic interview, but what if it could be diagnosed before the first symptom emerged? Researchers at the Del Monte Institute for Neuroscience at the University of Rochester are pointing toward a potential biomarker in the brain that could lead to more timely interventions and personalized care.

25 Nov 2024

Dopamine and serotonin balance reward learning in opposing ways

If you've heard of two of the brain's chemical neurotransmitters, it's probably dopamine and serotonin. Never mind that glutamate and GABA do most of the work - it's the thrill of dopamine as the "pleasure chemical" and serotonin as tender mood-stabilizer that attract all the headlines.

25 Nov 2024

Multiomic signatures identified for rapid detection and treatment of high-risk T-ALL

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered the underlying biology that identifies a subset of patients with acute lymphoblastic leukemia who have a higher risk version of the disease and are more likely to relapse despite treatment.

25 Nov 2024

Temozolomide and radiation combination improves survival in low-grade glioma patients

Both radiation and temozolomide, a generic chemotherapy treatment in pill form, have meaningful single-modality anti-tumor activity against slow-growing, low-grade gliomas.

25 Nov 2024

Study highlights barriers to long-term recovery for opioid use disorder patients

A new study led by Thomas Jefferson University researchers highlights critical healthcare gaps that hinder long-term recovery for people living with opioid use disorders (OUD) in Philadelphia.

25 Nov 2024

New discovery in the peripheral nervous system could help control obesity

An international team of researchers has discovered a new component of the peripheral nervous system that acts by increasing energy metabolism in the body.

25 Nov 2024

Knowing your family health history is key to reducing heart attack or stroke risk

Research shows that as much as half of your risk for heart disease can come from your family genes. Experts from the American Heart Association, celebrating a century of lifesaving service as the world's leading nonprofit organization focused on heart and brain health for all, say knowing your family health history is an important step to reducing your risk for a heart attack or stroke.

25 Nov 2024

Researchers identify brain circuit behind sexual rejection in females

A team from the Champalimaud Foundation (CF) has pinpointed a critical neural circuit for sexual rejection, identifying a set of brain cells that play a crucial role in determining whether a female accepts or rejects mating attempts based on her reproductive cycle.

25 Nov 2024