Gen-Probe to merge industrial testing assets into an independent company

Gen-Probe Incorporated (Nasdaq: GPRO) announced today that it is spinning off its industrial testing assets into a new, independent company focused on developing rapid, highly accurate molecular assays for biopharmaceutical production, water and food safety testing, and other applications.

Gen-Probe initially will own 19.9% of the new company, Roka Bioscience, Inc. Affiliates of leading private equity firms OrbiMed Advisors, TPG (TPG Biotechnology) and New Enterprise Associates have agreed to provide Roka up to $37.2 million in aggregate equity funding to complete development of several industrial assays and Gen-Probe's Closed Unit Dose Assay (CUDA) system, a fully integrated, portable testing instrument that can deliver highly accurate molecular results in approximately one hour.

"We believe establishing a highly focused, standalone company is the best way to maximize the considerable long-term potential of our molecular technologies in industrial markets," said Carl Hull, Gen-Probe's president and chief executive officer (CEO). "Our ownership position enables us to participate in Roka's long-term success, while allowing us to concentrate Gen-Probe's internal resources and core competencies on clinical opportunities in infectious disease testing, blood screening, transplant diagnostics and oncology."

Eighteen former Gen-Probe employees with expertise in industrial fields have joined Roka, which will begin operating as an independent company immediately. Gen-Probe also will contribute to Roka its CUDA system, other industrial assets, and the right to use certain of its technologies and related know-how in industrial markets. In addition to biopharmaceutical production and water and food safety testing, these markets include veterinary, environmental and bioterrorism testing. Roka also will have rights to develop certain infection control tests for use on the CUDA system.

Gen-Probe will receive royalties on any potential Roka product sales, and retain rights to use the CUDA system for clinical applications. In addition, Gen-Probe will provide contract manufacturing and certain other services to Roka on a transitional basis.

The spin-off is expected to have no material effect on Gen-Probe's 2009 earnings, as reductions in operating expenses will be offset by lower collaborative research and product revenues.

Gen-Probe's industrial testing collaborators, Millipore and GE Water (a division of GE Energy, a business unit of General Electric), have agreed to the transfer of their respective collaborations with Gen-Probe to Roka. Gen-Probe's collaboration with Millipore is focused on developing microbial detection assays to ensure the purity of biopharmaceutical production processes, while the Company is working with GE to develop rapid molecular tests to detect microbial contamination in industrial water.

Roka's CEO is Paul G. Thomas, an experienced healthcare executive who recently was chairman, president and CEO of LifeCell Corporation, a regenerative medicine company, before it was sold to Kinetic Concepts, Inc., for $1.8 billion in 2008. During his tenure at LifeCell, annual product revenues increased from $7.2 million in 1998, to $190 million in 2007.

"I am excited to have the opportunity to lead a talented group of scientists and engineers who are striving to revolutionize industrial testing markets with high-performance molecular assays and systems," Mr. Thomas said. "We will pursue our shared vision based on a robust technology platform, two top-notch commercial partners, and strong financial backing."