N-of-One, Inc., provider of Diagnostic Strategy Roadmaps™ and Treatment
Strategy Roadmaps™ for personalized cancer care, announced today that
the company has developed a unique knowledge integration platform to
enable care providers and patients to make informed decisions about
diagnostic and treatment strategy. The platform, called PrecisionWorks™,
is designed to empower physicians to deliver personalized care for every
cancer patient.
"We're living in a time of unprecedented opportunity to transform cancer
treatment and outcomes, driven by rapid advances in our understanding of
molecular biology, genomics, and related technologies," said Jennifer
Levin Carter, MD, MPH, Founder, President, and Chief Medical Officer of
N-Of-One. "Now that we have the knowledge and technologies required to
more precisely tailor treatment by targeting molecular drivers of each
patient's disease, the real challenge has been in putting the relevant
capabilities effectively into clinical practice."
PrecisionWorks powers clinically actionable deliverables that help
medical teams make the most informed decisions possible when
individualizing diagnostic and treatment strategy. N-of-One's solutions,
created by the company's team of oncologists and scientists, include:
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Diagnostic Strategy Roadmaps identify key relevant biomarkers
to be evaluated in each patient's specific tumor type, based on the
latest molecular oncology research and on targeted treatments
available for those biomarker alterations. N-of-One coordinates
testing at top CLIA-approved diagnostic laboratories.
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Treatment Strategy Roadmaps link positive biomarkers identified
in the patient's tumor to targeted therapies that may be effective
against the patient's specific cancer, all within the context of the
individual's other known molecular alterations and relevant disease
history.
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MarkerMatch™ matches patients with current clinical trials that
are relevant to their particular cancer type and molecular profile.
N-of-One has evolved PrecisionWorks since the company's launch in 2008
to integrate and streamline the fast-moving, data-intensive realm of
cancer research, diagnostics, and treatment. While the company's early
focus has been on the direct-to-consumer needs of individual cancer
patients, PrecisionWorks provides a new level of functionality designed
to meet the needs of physicians and healthcare providers to access the
very latest knowledge and technologies they need, when they need them,
to individualize diagnostic and treatment decisions for each patient.
"We've always believed in tackling the complexity of the personalized
oncology system from the perspective of the individual patient, and
initially, we worked directly with patients to deliver our knowledge
platform and solutions for accessing personalized care," said Dr.
Carter. "Over time, we have evolved and optimized PrecisionWorks from a
direct-to-patient approach into an integrated, systematized platform
that enables us now to expand access to much larger groups of patients
through oncologists, regional cancer centers, provider networks, and
diagnostic laboratories, while still providing our direct-to-patient
solutions. In addition to delivering PrecisionWorks to providers at the
point of care, N-of-One is implementing a partnering strategy with
diagnostic companies that draws on selective components of the
PrecisionWorks platform to transform the molecular alteration data from
their tests into customized, clinically relevant reports that help
clinicians better understand and act upon the test results."
The PrecisionWorks platform integrates:
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MarkerMine™, a comprehensive molecular knowledge database that
brings together two types of data not previously integrated in
healthcare management: Individual patient data, and the latest
molecular knowledge about cancer
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Advanced analytic capabilities for synthesizing and
transforming different types of information (including molecular,
genomic, patient, therapeutic, diagnostic, population, etc.) into
patient-specific knowledge that drives a targeted-care approach
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Logistics management systems to address the unique logistical
and procedural challenges of delivering personalized cancer care by
simplifying coordination among health care providers, diagnostic
companies, payers, drug companies, and patients
"Healthcare providers need these capabilities now to provide their
patients access to the same leading-edge, data-driven knowledge and
decision-support tools as the field's top experts," said Christine
Cournoyer, Chief Executive Officer of N-of-One. "What we're providing
today are services and solutions that allow providers to more rapidly
and cost effectively deploy the knowledge and resources they need to
improve patient outcomes through precision oncology."