Excess mortality from COVID-19 is the highest since 1918

Excess mortality is defined as the comparison between the expected and observed mortality values. The “expected” mortality value is obtained by extrapolating observations from events that have occurred in previous years.

Study: Pandemic excess mortality in Spain, Sweden, and Switzerland during the COVID-19 pandemic in 2020 was at its highest since 1918. Image Credit: Cryptographer / Shutterstock.com

The utility of excess mortality estimates

Excess mortality has been used by demographers since the 1830s and can be applied both temporally or regionally. In the current coronavirus disease 2019 (COVID-19) pandemic, excess mortality is increasingly used to determine both the direct and indirect impacts of this disease. In fact, various global estimates, including those provided by the World Health Organization (WHO), show that excess mortality significantly exceeded official COVID-19 death reports by up to several million.

A recent study published on the preprint server medRxiv* provides an assessment of the ongoing pandemic, as well as other pandemic periods since the end of the 19th century, by estimating age-specific monthly all-cause excess deaths in Sweden, Switzerland, and Spain.

These three countries were well suited for contextualization of excess mortality, as continuous data from 100 years or more were available. Additionally, these countries were military neutral throughout much of this century, thereby eliminating the potentially confounding factor of war-impacted excess mortality on these estimates.

These countries were also not affected by significant territory shifts since the end of the 19th century. Another similarity between Sweden, Switzerland, and Spain is that each of these nations was highly affected by the 2020 pandemic.

About the study

In the current study, the researchers analyzed the monthly all-cause deaths, which is defined as the officially reported deaths. The earliest available year for these values was 1908, 1851, and 1877 in Spain, Sweden, and Switzerland, respectively. The end date for all three nations was December 31, 2020.

The years with high pandemic mortality (1890, 1918, 1957) were excluded from the study. Additionally, the month and age-group-specific overall death counts were estimated. Negative binomial and multinomial likelihoods were used for the two counts, whereas annual population counts were used as offsets.

Study findings

The current study showed that the excess mortality counts of 2020 were much higher as compared to the 1918 influenza pandemic in Switzerland and Sweden. This was also the case for Spain when COVID-19 deaths were compared to death counts during the Spanish civil wars.

In all three countries, the peaks of monthly excess mortality in 2020 were significantly higher than any monthly excess mortality since 1918. These excess mortality values also considered all seasonal flu peaks and heatwaves during this time.

The study also showed that during the last three pandemics, high excess mortality levels were observed during the same time of the year in all three countries. However, in the case of the COVID-19 pandemic, the two waves affected each country differently.

In the 1918 pandemic, for example, young adults were found to be at a greater risk of death. Comparatively,  the COVID-19 pandemic primarily affected older adults in all three countries.

Excess all-cause deaths by age group for deadliest pandemic years 1890, 1918, 1957, and 2020 for all 3 countries. The number of excess deaths with 95% credible intervals are scaled by the number of expected deaths in each age group.

Taken together, the researchers found that while there are parallels that can be drawn between the current pandemic and previous outbreaks, these comparisons with prior pandemics should be made cautiously.

Conclusion

Notably, age, sex, and cause-specific monthly death statistics were not available for several years of the 20th century. The impact of the civil war in Spain was also not completely quantified. An additional limitation of the current study is that not all religions from the three countries were equally affected by COVID-19, which may hide regional nuances.

“Following the evidence on excess mortality, the 2020 pandemic led to the second largest demographic disaster in over 100 years in the three countries we studied. Looking beyond these 3 countries to other European ones shows that such excess mortality in 2020 was by no means inevitable.”

*Important notice

medRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or treated as established information.

Journal reference:
Suchandrima Bhowmik

Written by

Suchandrima Bhowmik

Suchandrima has a Bachelor of Science (B.Sc.) degree in Microbiology and a Master of Science (M.Sc.) degree in Microbiology from the University of Calcutta, India. The study of health and diseases was always very important to her. In addition to Microbiology, she also gained extensive knowledge in Biochemistry, Immunology, Medical Microbiology, Metabolism, and Biotechnology as part of her master's degree.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Bhowmik, Suchandrima. (2021, August 18). Excess mortality from COVID-19 is the highest since 1918. News-Medical. Retrieved on October 24, 2021 from https://www.news-medical.net/news/20210818/Excess-mortality-from-COVID-19-is-the-highest-since-1918.aspx.

  • MLA

    Bhowmik, Suchandrima. "Excess mortality from COVID-19 is the highest since 1918". News-Medical. 24 October 2021. <https://www.news-medical.net/news/20210818/Excess-mortality-from-COVID-19-is-the-highest-since-1918.aspx>.

  • Chicago

    Bhowmik, Suchandrima. "Excess mortality from COVID-19 is the highest since 1918". News-Medical. https://www.news-medical.net/news/20210818/Excess-mortality-from-COVID-19-is-the-highest-since-1918.aspx. (accessed October 24, 2021).

  • Harvard

    Bhowmik, Suchandrima. 2021. Excess mortality from COVID-19 is the highest since 1918. News-Medical, viewed 24 October 2021, https://www.news-medical.net/news/20210818/Excess-mortality-from-COVID-19-is-the-highest-since-1918.aspx.

Comments

  1. Richard Eisenman Richard Eisenman United States says:

    its "regions", not "religions".

    and comparison with 1918 excess death rates of order 200% with 2020 excess death rates of order 20% is idiotic. Not to mention that loss of QALYs would be an additional order of magnitude higher in 1918 due to "spanish flue" affecting a far younger demographic (vs covid average mortality aroung age ~80).

    Anyway, sorry to be so critical, but doesn't this medical web site have an editor? Putting half baked articles like this out is just adding chaos and noise to legitimate public health concerns.

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
You might also like... ×
Analysis of SARS-CoV-2 Delta variant transmissibility across New England, USA