Insulin Resistance News and Research

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Insulin Resistance is a condition in which the body does not respond to insulin properly. This is most common in Type II diabetes or associated with obesity, ketoacidosis, infection, and certain rare conditions. Diminished effectiveness of insulin in lowering blood glucose levels requiring 200 units or more of insulin per day to prevent hyperglycemia or ketosis.

Study shows how ketogenic eating improves hormonal balance in PCOS

The very low-carbohydrate ketogenic diet leads to meaningful reductions in weight, visceral adiposity, insulin resistance, and androgen excess in women with PCOS based on pooled randomized trials. Benefits appear consistent across studies, though high heterogeneity, short durations, and limited safety data highlight the need for longer-term comparative research.

19 Nov 2025

Study explores how elevated growth hormone levels contribute to liver aging

A new research paper was published in Volume 17, Issue 10 of Aging-US on October 3, 2025, titled "Growth hormone excess drives liver aging via increased glycation stress."

18 Nov 2025

Daily black cumin intake improves blood lipids and reduces obesity risk

Nigella sativa (black cumin), the spice that boosts the flavor of curries like korma and paneer also has another use: its seeds have long been used as a medicinal plant in traditional medicine for their antioxidant and anti-inflammatory effects.

18 Nov 2025

Are mushrooms more than a low-calorie food? New analysis explains their hidden advantages

Whole mushroom consumption shows consistent benefits for cardiometabolic health, lowering triglycerides in self-chosen diets and improving fasting glucose in a single healthy dietary pattern trial. Early evidence also suggests increases in salivary IgA and possible blood pressure improvements, with no adverse biomarker effects reported.

16 Nov 2025

Dash diet cuts diabetes complications by targeting blood pressure kidney health and inflammation

The DASH diet supports metabolic health in people with diabetes by improving blood pressure, renal function, lipids, and modest glycemic markers while reducing risks linked to vascular and inflammatory pathways. Its broad nutrient-driven mechanisms also benefit related conditions such as neuropathy, PCOS, and retinopathy, making it a versatile tool for cardiometabolic care.

16 Nov 2025

Understanding leptin's dual function in MAFLD pathogenesis

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, intricately linked with obesity, type 2 diabetes (T2DM), and metabolic syndrome.

14 Nov 2025

Doubling rates of childhood hypertension signal urgent health concern

The rate of children and adolescents experiencing high blood pressure worldwide nearly doubled between 2000 and 2020, according to a new meta-analysis published in The Lancet Child & Adolescent Health journal.

12 Nov 2025

Exosomes identified as key mediators in obstructive sleep apnea and its comorbidities

Obstructive sleep apnea (OSA), a global public health issue marked by repeated upper airway collapse during sleep, is tied to diverse diseases-from cardiovascular conditions to cancer.

12 Nov 2025

Ultra-processed food consumption increases the risk for prediabetes in young adults

More than half of calories consumed in the United States come from ultra-processed foods (UPFs), items like fast food and packaged snacks that are often high in sodium, sugar and unhealthy fats.

10 Nov 2025

Weill Cornell scientists discover early step in fat cell inflammation leading to diabetes

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

10 Nov 2025

Genetic and cellular mechanisms underlying steatotic liver disease

Steatotic liver disease (SLD), mainly encompassing metabolic dysfunction-associated steatotic liver disease (MASLD), alcohol-related liver disease (ALD), and metabolic dysfunction and ALD (MetALD), has emerged as the dominant cause of chronic liver disease worldwide, displacing viral hepatitis as the primary aetiology.

10 Nov 2025

How diet affects aging metabolism differently for men and women

Research reveals sex-based differences in diet's impact on metabolism, highlighting plant proteins for men and moderate wine for women in older adults.

7 Nov 2025

Resistance exercise may offer greater benefits for preventing diabetes and obesity

Running may help burn calories, but when it comes to preventing diabetes and obesity, pumping iron might have the edge, according to preclinical findings from the Fralin Biomedical Research Institute at VTC.

4 Nov 2025

Research shows citrus and grape compounds may protect against type 2 diabetes

A six-month clinical trial found that a supplement combining citrus and grape extracts, hesperidin, and chromium significantly reduced fasting blood glucose in prediabetic adults. Participants also saw improved cholesterol and triglyceride levels, returning many to normal metabolic health.

2 Nov 2025

Refugees will be among the first to lose food stamps under federal changes

After fleeing the war-torn Democratic Republic of Congo, Antoinette landed in the Atlanta area last November and began to find her footing with federal help.

30 Oct 2025

Four distinct subgroups of PCOS open up for more tailored treatments

Four distinct subgroups of polycystic ovary syndrome (PCOS) have been identified in an international study published in Nature Medicine by researchers from Karolinska Institutet, among others.

29 Oct 2025

Are ultra-processed plant foods really worse than meat? Scientists weigh in

A new review challenges assumptions about ultra-processed foods, finding that plant-based versions, such as soymilk, meat analogs, and soft margarines, may lower cholesterol and disease risk compared with unprocessed animal foods when used as replacements.

26 Oct 2025

Semaglutide can offer important heart benefits that go beyond weight loss

A new analysis of the SELECT trial – the largest and longest clinical trial to date examining the cardiovascular benefits of semaglutide (a medication used to support weight loss and diabetes management) – confirms it also lowers the risk of major heart problems in people who are overweight or obese and already have heart disease, even if they don't have diabetes.

23 Oct 2025

Intensive program leads to high type 2 diabetes remission in India

Nearly one-third of people with type 2 diabetes (T2D) in an Indian cohort achieved remission through an intensive lifestyle intervention program, according to a new study publishing October 22, 2025, in the open-access journal PLOS One by Pramod Tripathi of Freedom from Diabetes Clinic & Diabetes Research Foundation, India, and colleagues.

23 Oct 2025

Can strawberries help prevent diabetes? New trial shows promising results in prediabetic adults

Daily consumption of freeze-dried strawberries for 12 weeks improved antioxidant defense, reduced inflammation, and lowered fasting glucose in adults with prediabetes. The randomized crossover trial highlights strawberries’ potential as a simple, food-based strategy to enhance metabolic and vascular health.

21 Oct 2025