Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025

Scientists engineer new drug candidate to fight deadly mycobacterial infection

In a classic example of scientific problem solving, scientists from the Hackensack Meridian Center for Discovery and Innovation (CDI) and colleagues have published a paper introducing a promising new drug candidate they engineered to target a deadly and emerging infection.

6 May 2025

Research reveals how psychedelics reshape communication between the brain and immune system

In a compelling Genomic Press interview published today, rising scientific star Dr. Michael Wheeler unveils revolutionary findings about how psychedelics reshape communication between the brain and immune system, potentially transforming treatments for psychiatric disorders and inflammatory diseases alike.

6 May 2025

New gene editing tool enables precise control of mitochondrial mutation load

Mitochondrial diseases affect approximately 1 in 5,000 people worldwide, causing debilitating symptoms ranging from muscle weakness to stroke-like episodes.

3 May 2025

Study links impaired synaptic pruning to autism

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition in which affected individuals experience difficulties in social communication and exhibit restricted, repetitive patterns of behavior or interests.

30 Apr 2025

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Metrion Biosciences ("Metrion"), the specialist preclinical contract research organization (CRO) and a global leader in ion channel services, today announced the launch of its validated, high-throughput NaV1.9 screening assay to advance discovery and development of novel pain therapeutics.

28 Apr 2025

Research uncovers the cellular culprit behind age-related abdominal fat

It's no secret that our waistlines often expand in middle-age, but the problem isn't strictly cosmetic. Belly fat accelerates aging and slows down metabolism, increasing our risk for developing diabetes, heart problems and other chronic diseases.

25 Apr 2025

Researchers pioneer method to measure liver tissue stiffness without damage

Researchers in South Korea have developed an organoid disease model and non-destructive stiffness analysis technology for evaluating the efficacy of new drugs for fatty liver disease.

25 Apr 2025

CN Bio and Pharmaron establish long-term strategic partnership to develop OOC technologies on a global R&D platform

CN Bio, a leading provider of Organ-on-a-chip systems and solutions that accelerate drug discovery and development workflows, today announced the establishment of a strategic partnership with Pharmaron, a premier R&D service provider for the life sciences industry.

24 Apr 2025

Mosaic Therapeutics in-licenses two clinical-stage oncology programs from Astex Pharmaceuticals for development as proprietary combination therapies

Mosaic Therapeutics, Ltd ('Mosaic') a targeted oncology therapeutics company dedicated to resolving cancer's complexity with new combination therapies for patients, today announces the in-licensing of two clinical-stage oncology programs from Astex Pharmaceuticals ('Astex'), a wholly owned subsidiary of Otsuka Pharmaceutical Co. Ltd.

24 Apr 2025

Scientists develop promising new drug candidates against coronaviruses

A team at UC San Francisco and Gladstone Institutes has developed new drug candidates that show great promise against the virus that causes COVID-19 and potentially other coronaviruses that could cause future pandemics.

23 Apr 2025

San Antonio scientists use machine learning to identify potential treatments for deadly viruses

A team of San Antonio-based biomedical researchers trained a machine learning algorithm to identify more than two dozen viable treatments for diseases caused by zoonotic pathogens that can jump from animal hosts to infect humans.

23 Apr 2025

DNA origami structures enable targeted imaging of pancreatic cancer

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue.

22 Apr 2025

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity-two issues that commonly co-occur with alcohol use disorder (AUD).

22 Apr 2025

Boost your transfection success with these proven expert tips

Gain expert insights in this interview on achieving transfection success. Explore proven strategies to optimize your approach and enhance results.

From Sartorius 22 Apr 2025

Major breakthrough could turn IV drugs into oral treatments for brain cancer and Alzheimer's

A research team led by scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) made a major breakthrough with the potential to turn IV drugs into oral treatments for diseases like brain cancer and Alzheimer's disease.

21 Apr 2025

New discovery enhances cell entry for complex cancer drugs

A new discovery could pave the way for more effective cancer treatment by helping certain drugs work better inside the body.

17 Apr 2025

Researchers simulate protein structures behind learning and memory

Our brain's remarkable ability to form and store memories has long fascinated scientists, yet most of the microscopic mechanisms behind memory and learning processes remain a mystery.

16 Apr 2025

Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing

Researchers used integrated Mendelian randomization in a cohort of over 247,000 individuals to identify 62 plasma proteins associated with breast cancer risk. Nine high-confidence targets, including ULK3 and CSK, showed potential for drug repurposing and immune pathway regulation.

16 Apr 2025

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

CellVoyant leverages AI and live-cell imaging to predict cellular behavior, transforming cell therapy development and making it more accessible and efficient.

16 Apr 2025

Drug Discovery News and Research

Further Reading

Precision medicine approach improves treatment for soft tissue sarcomas

Scientists engineer new drug candidate to fight deadly mycobacterial infection

Research reveals how psychedelics reshape communication between the brain and immune system

New gene editing tool enables precise control of mitochondrial mutation load

Study links impaired synaptic pruning to autism

Metrion Biosciences launches NaV1.9 high-throughput screening assay to strengthen screening portfolio and advance research on new medicines for pain

Research uncovers the cellular culprit behind age-related abdominal fat

Researchers pioneer method to measure liver tissue stiffness without damage

CN Bio and Pharmaron establish long-term strategic partnership to develop OOC technologies on a global R&D platform

Mosaic Therapeutics in-licenses two clinical-stage oncology programs from Astex Pharmaceuticals for development as proprietary combination therapies

Scientists develop promising new drug candidates against coronaviruses

San Antonio scientists use machine learning to identify potential treatments for deadly viruses

DNA origami structures enable targeted imaging of pancreatic cancer

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

Boost your transfection success with these proven expert tips

Major breakthrough could turn IV drugs into oral treatments for brain cancer and Alzheimer's

New discovery enhances cell entry for complex cancer drugs

Researchers simulate protein structures behind learning and memory

Researchers link 9 blood proteins to breast cancer and suggest 3 drugs for repurposing

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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