Pathology News and Research

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Pathology is the study and diagnosis of disease through examination of organs, tissues, bodily fluids, and whole bodies (autopsies). The term also encompasses the related scientific study of disease processes, called General pathology. Medical pathology is divided in two main branches, Anatomical pathology and Clinical pathology. Veterinary pathology is concerned with animal disease whereas Phytopathology is the study of plant diseases.

BWH researchers identify new rare genetic cause of peritoneal mesothelioma

Mesothelioma is a rare and aggressive tumor that, in many cases, results from exposure to asbestos. But over the last several decades, other causes of the disease have emerged, including treatment with high-intensity therapeutic radiation and, more recently, an inherited genetic mutation.

14 Sep 2017

Abnormalities in common brain chemical linked to sudden infant death syndrome

University of Adelaide researchers have confirmed that abnormalities in a common brain chemical are linked to sudden infant death syndrome (SIDS).

14 Sep 2017

Researchers discover important link between Parkinson's and prion diseases

Parkinson's disease and prion diseases are very different from each other as regards both origins and course. Nonetheless, a research group of SISSA's, headed by Professor Giuseppe Legname, has discovered an unexpected and important link between the two pathologies.

14 Sep 2017

Probiotics may become new preventative or therapeutic strategy for IBD-related colon cancer

In an innovative approach to colorectal cancer (CRC) prevention and treatment, scientists are studying ways to replace missing metabolites in patients prone to gut inflammation and CRC.

14 Sep 2017

Study reveals how nitric oxide impedes growth of ‘snail fever’ parasite

Bilharzia, caused by a parasitic worm found in freshwater called Schistosoma, infects around 200 million people globally and its advance can lead to death, especially in children in developing countries.

14 Sep 2017

New tissue clearing technique makes human organs transparent to enhance pathological diagnosis

To some, the idea of invisibility leads to mischief, seeing things without being seen. To the pathologist, the idea of invisibility leads to simplicity, seeing the disease in its fullest.

13 Sep 2017

New method can offer cost-effective solution to assess OSA risk and severity

Obstructive sleep apnea syndrome (OSA) affects approximately 34% of men and 17% of women within the adult population. Although sex, aging, and obesity are the main factors associated with OSA, research has shown that larger tongue, lateral pharyngeal walls, tonsils, soft palate, and total pharyngeal soft tissue volumes can also be considered OSA risks. Prior research has largely relied on calipers, which are used to measure the oral cavity and craniofacial dimensions of subjects, but there are limited data on reproducibility, and the process is generally considered cumbersome and unpleasant.

12 Sep 2017

Researchers set new delivery distance record for medical drones

Johns Hopkins researchers have set a new delivery distance record for medical drones, successfully transporting human blood samples across 161 miles of Arizona desert. Throughout the three-hour flight, they report, the on-board payload system maintained temperature control, ensuring the samples were viable for laboratory analysis after landing.

12 Sep 2017

Genome sequence cannot predict radiation resistance, say researchers

For the last two decades, researchers worldwide have been using whole genome sequencing to understand what makes cells radiation-resistant, hoping to solve an old biological mystery: why is it that one of the most radiation-resistant organisms, Deinococcus radiodurans, aka "Conan the bacterium," can survive hundreds of times more DNA damage caused by gamma rays than most other organisms? According to a study published recently in Standards of Genomic Sciences by researchers at the Uniformed Services University (USU), the amount of radiation a Deinococcus cell can survive in fact has little to do with the number and types of its DNA repair proteins.

11 Sep 2017

Researchers discover major mechanism in development of liver cancer

Liver cancer is the second-leading cause of cancer-related death and represents the fastest rising cancer worldwide. In most cases, the tumor develops in patients with chronic liver disease.

11 Sep 2017

Compounds in fermented fish paste inhibit enzyme involved in cholesterol synthesis

Compounds in a fermented fish paste used as a condiment in Indonesia efficiently inhibit an enzyme involved in cholesterol synthesis, reports a study published in the Pertanika journal Tropical Agricultural Science.

11 Sep 2017

Retinal imaging may help doctors confirm or rule out frontotemporal degeneration

Frontotemporal degeneration (FTD) is a progressive neurodegenerative condition that is present in tens of thousands of Americans, but is often difficult to diagnose accurately.

8 Sep 2017

UCLA awarded $8.4 million NIH grant to improve outcomes for liver transplant recipients

UCLA has received an $8.4 million grant from the National Institutes of Health to research ways to help donated livers last longer and improve outcomes for transplant recipients.

8 Sep 2017

Researchers define how cancer drug works in cells, mice and man

Science is very good at determining how drugs work in experimental models. New research out of Dartmouth's Norris Cotton Cancer Center led by Alan Eastman, PhD, helps to bridge the gap when it comes to ensuring that drugs work by the same mechanism in human patients.

7 Sep 2017

Breakthrough study could lead to diagnostic tools and better treatments for chronic bronchitis

When a patient arrives at a doctor's office with a persistent cough and the sensation of gunk building up in the lungs, the doctor's thought process is essentially the same as it would have been decades ago. There has been no understanding of the affected biological pathways causing the gunk buildup in the lung, nor has there been a diagnostic test for chronic bronchitis.

7 Sep 2017

Genetic risk for obesity influenced by lifestyle, study shows

The risk for developing obesity is influenced by our lifestyle as well as our genes. In a new study from Uppsala University, researchers show that our genetic risk for obesity is not static, but is influenced by our lifestyle. Results from the study have been published in the scientific journal PLOS Genetics.

6 Sep 2017

Zika virus may one day be effective treatment for deadly brain cancer

While Zika virus causes devastating damage to the brains of developing fetuses, it one day may be an effective treatment for glioblastoma, a deadly form of brain cancer.

5 Sep 2017

Anyslide by microDimensions provides a cloud-based digital pathology platform

Digital Pathology is happening. While the advantages are evident and experts already predict a new generation of pathologists, only few laboratories and institutes have started planning and investing in fully digital work-flows. At the same time, the demand for professional online exchange and a convenient way of sharing educational or rare cases is growing with the aim to support a more precise and profound health care.

From microDimensions - Bramlage Scientific GmbH 5 Sep 2017

Japanese scientists uncover new genetic marker for schizophrenia

Schizophrenia is a complicated disease that often appears in early adulthood. Although scientists have not traced the genetic causes, more than 80% of schizophrenia cases are considered to have a hereditary cause.

5 Sep 2017

New method of genetic testing leads to successful targeting of MET fusion in lung cancer

There are many ways a gene can be altered and there are many genes that, when altered, can cause cancer. Testing individually for each possible alteration in every cancer-related gene is not feasible as it would require hundreds of individual tests and many, many thousands of dollars.

31 Aug 2017