Tissue Engineering News and Research

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Dramatic advances in the fields of biochemistry, cell and molecular biology, genetics, biomedical engineering and materials science have given rise to the remarkable new cross-disciplinary field of tissue engineering. Tissue engineering uses synthetic or naturally derived, engineered biomaterials to replace damaged or defective tissues, such as bone, skin, and even organs.

Pioneering technology enables scalable production of human kidney organoids

A research team led by the Institute for Bioengineering of Catalonia (IBEC) and collaborating with the Biomedical Research Institute of A Coruña (INIBIC), as well as other international research groups, has developed pioneering technology that enables human kidney organoids to be produced in a scalable manner.

31 Oct 2025

Advancements in organoids could transform treatment of spinal cord injury and peripheral nerve injury

A recent review published in Engineering explores the construction and potential applications of spinal cord and peripheral nerve organoids for regenerative medicine in neurotrauma.

24 Oct 2025

Discovering the role of lingual and buccal cells in tooth development

A novel study on the natural coordination of tooth development in time and space, led by Dr. Han-Sung Jung at the Yonsei University College of Dentistry, Korea, has discovered that "lingual" cells on the side of the tongue form the tooth, whereas those toward the cheek, called "buccal cells," form the bones and gums, guided by signaling molecules like WNT and BMP.

24 Oct 2025

New nanomanufacturing technique enhances vascular systems in artificial human tissue

When biomedical researchers need to test their latest ideas, they often turn to engineered human tissue that mimics the responses in our own bodies. It's become an important intermediary step before human clinical trials.

16 Oct 2025

Natural sweetener improves hair loss treatment

Androgenetic alopecia is a common form of hair loss in both men and women-also called male pattern baldness and female pattern hair loss.

9 Oct 2025

Nanotechnology breakthrough reverses Alzheimer’s disease in mice

A research team co-led by the Institute for Bioengineering of Catalonia (IBEC) and West China Hospital Sichuan University (WCHSU), working with partners in the UK, has demonstrated a nanotechnology strategy that reverses Alzheimer's disease in mice.

6 Oct 2025

Engineers create designer biobots using human lung cells

A brand-new engineering approach to generate "designer" biological robots using human lung cells is underway in Carnegie Mellon University's Ren lab.

26 Sep 2025

New microfluidic-based biosensing platform helps track live antibody secretion dynamics

A research team at the Terasaki Institute, led by Dr. Vadim Jucaud in collaboration with Dr. Jing Yong Ye from the University of Texas San Antonio, has developed a new microfluidic-based biosensing platform that allows monitoring cellular secretion of monoclonal antibody in real time.

23 Sep 2025

Penn State team develops wearable sensor to track health through minimal sweat

Available on-demand, in abundance and containing multiple biomarkers, sweat is an increasingly appealing medium for monitoring health, according to researchers at Penn State.

3 Sep 2025

Novel vascularized cancer-on-a-chip model reflects the microenvironment of liver tumors

Dr. Vadim Jucaud's lab at the Terasaki Institute has developed a human vascularized liver cancer-on-a-chip model to evaluate vessel remodeling and cell death in response to embolic agents.

3 Sep 2025

Researchers develop a 3D-bioprinted in vitro model of stenotic brain blood vessels

Cerebrovascular diseases such as atherosclerosis and stroke remain a major cause of morbidity and mortality worldwide.

19 Aug 2025

Vagus nerve modulation can effectively halt the progression of cancer-associated cachexia

The Terasaki Institute for Biomedical Innovation announces a significant advancement in addressing the fight against cancer-associated cachexia (CAC), a life-threatening syndrome responsible for over one-third of cancer-related deaths.

14 Aug 2025

Scaffold-free cellular spheroids generate integrated osteochondral grafts

A new study in the peer-reviewed journal Tissue Engineering, Part A demonstrates the potential to produce cellular spheroids, from a clinically relevant embryonic stem cell derived mesenchymal stem cell (ES-MSC) source, to generate scaffold-free chondrogenic or osteochondrogenic graft tissues.

14 Aug 2025

Bioactive fiber scaffold shows promise for bone defect repair

Bone defects are a major challenge in regenerative medicine, often requiring advanced biomaterials to enhance the natural healing process.

8 Aug 2025

Study unveils a novel therapeutic solution for diabetic wound healing

Diabetic wounds, particularly foot ulcers, are notorious for their slow and often incomplete healing due to reduced blood flow and endothelial cell dysfunction.

8 Aug 2025

Novel hydrogel accelerates infected wound repair with antibacterial properties

A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. This multifunctional injectable hydrogel delivers robust antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.

8 Aug 2025

Mechanical stretching boosts stem cell therapy for diabetic wounds

Chronic wounds, especially those caused by diabetes, are notoriously difficult to heal. These wounds are characterized by prolonged inflammation, impaired collagen production, and poor tissue regeneration.

7 Aug 2025

Copper oxide scaffolds show promise in treating traumatic brain injury

Traumatic brain injury (TBI) remains one of the leading causes of disability worldwide. Recent research has developed a novel electrospun scaffold loaded with copper oxide (CuO@PG), which aims to restore copper homeostasis and modulate inflammation in TBI.

7 Aug 2025

Multifunctional hydrogel offers new hope for diabetic wound healing

Diabetes is a global epidemic, and its complications—particularly chronic wounds—are both debilitating and costly.

7 Aug 2025

Columbia engineers create bioactive hydrogels using dairy-derived EVs

Researchers from Columbia Engineering have established a framework for the design of bioactive injectable hydrogels formulated with extracellular vesicles (EVs) for tissue engineering and regenerative medicine applications.

28 Jul 2025