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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Review finds correlation between milk oligosaccharides and infant brain development

In a recent article published in Nutrients, researchers investigated the current evidence of the impact of milk oligosaccharides (MOS) on early life neurocognitive and brain development.

30 Aug 2023

Study suggests whole egg consumption has benefits over egg white consumption in young, healthy adults

Researchers investigated the impacts of different egg-based diets on healthy young individuals' immune, hematologic, and metabolic clinical profiles.

30 Aug 2023

AI-powered patient triage platform predicts COVID-19 severity and length of hospitalization

A team of researchers from Yale University and other institutions globally has developed an innovative patient triage platform powered by artificial intelligence (AI) that the researchers say is capable of predicting patient disease severity and length of hospitalization during a viral outbreak.

29 Aug 2023

Urine levels of adenine found to be predictive and causative biomarker of diabetic kidney disease

Urine levels of adenine, a metabolite produced in the kidney, are predictive and a causative biomarker of looming progressive kidney failure in patients with diabetes, a finding that could lead to earlier diagnosis and intervention, researchers from The University of Texas Health Science Center at San Antonio (also called UT Health San Antonio) reported Aug. 24 in the Journal of Clinical Investigation.

24 Aug 2023

High-fat diet changes gut bacteria, bile acids, and increases colorectal cancer risk

The prevalence of colorectal cancer in people under the age of 50 has risen in recent decades. One suspected reason: the increasing rate of obesity and high-fat diets.

22 Aug 2023

Melatonin enhances long-term memory by modulating protein phosphorylation

Multiple studies have demonstrated the memory-enhancing effects of melatonin and its derivatives in animal models. It is also known that the formation of both short- and long-term memories require the phosphorylation of certain memory-related proteins.

21 Aug 2023

New drug candidate nearly doubles survival for patients with aggressive childhood brain tumors

For the first time, researchers have found a potential drug candidate that improved outcomes for patients with a type of childhood brain tumor for which there are no effective treatments.

17 Aug 2023

Can nutritional interventions positively impact psoriasis severity?

Improvement in psoriasis (Ps) through nutritional strategies.

15 Aug 2023

A computational model identifies metabolites associated with Parkinson's disease

Researchers identify significant metabolites involved in the development and progression of Parkinson’s disease.

15 Aug 2023

New mechanism discovered for brain repair after ischemic stroke

Patients often experience functional decline after an ischemic stroke, especially due to the brain's resistance to regenerate after damage.

10 Aug 2023

Researchers discover novel breakthrough treatment for fungal infections

Researchers with the University of Oklahoma’s Natural Products Discovery Group recently published findings that indicate a novel breakthrough treatment for fungal infections.

7 Aug 2023

Gut microbiome changes have significant effects on cocaine use and cravings

According to the 2021 National Survey on Drug Use and Health, 4.8 million people (ages 12 and up) reported using cocaine within the previous 12 months, and 24,486 people died from an overdose involving cocaine.

3 Aug 2023

The mechanisms of triptan using metabolomics and transcriptomics in spontaneous migraine attacks

Researchers discuss the mechanisms of triptans for the treatment of spontaneous migraine attacks by using transcriptomics and metabolomics.

3 Aug 2023

High body temperature may boost gut microbiota to fight viral infections

Researchers from The University of Tokyo unravel the connection between high body temperature and increased viral resistance.

20 Jul 2023

Study examines the antibacterial properties of cinnamon and eucalyptus essential oils compared with their isolated major compounds

A comparison of the antibacterial properties of Cinnamonum cassia and Eucalyptus globulus to their most abundant bioactives metabolites.

20 Jul 2023

Meta-analysis confirms 17 key metabolites as strong predictors of gout

Researchers summarized the use of metabolomics to detect metabolites in gout patients.

18 Jul 2023

Understanding the impact of HPV on the vaginal microbiome and its role in cervical cancer

Researchers determine whether cervical cancer risk could be assessed using microflora-derived metabolites in HPV-infected females.

17 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Researchers uncover the role of glutaminase 2 in glucose homeostasis

Glutaminase 2 (GLS2) is a master regulator of glutaminolysis. GLS2 converts glutamine to glutamate, thereby playing a role in cellular energy production. GLS2 is abundant in the liver, and is also found in pancreatic β-cells. However, the role of GLS2 in pancreatic islets – in which both ɑ- and β- cells are present – associated with glucose metabolism is currently unknown.

5 Jul 2023

Exposure to tobacco smoke increases the presence of heavy metals in children's saliva, study shows

Secondhand tobacco smoke continues to be a major source of indoor air pollution that causes more than 41,000 nonsmoking adults to die every year in the United States, according to the Centers for Disease Control and Prevention.

29 Jun 2023