Oxidative Stress News and Research

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Oxidative Stress is a condition in which antioxidant levels are lower than normal. Antioxidant levels are usually measured in blood plasma.

APC-deficient cancer cells rely on single enzyme for survival

A newly published study reports that APC-deficient cancer cells may depend on a single metabolic enzyme for survival, revealing a potential strategy for selectively targeting tumours associated with one of the most common mutations in colorectal cancer.

20 Apr 2026

Fermentation boosts anti-inflammatory power in dairy alternatives

Investigating fermented oat and soy drinks, this study highlights their potential to enhance anti-inflammatory bioactivity through lipid transformation.

20 Apr 2026

Eating oranges daily may shift lipid patterns in fatty liver disease

A 4-week trial on 'Navelina' oranges shows potential effects on lipid metabolism in fatty liver disease, revealing intriguing but non-significant patterns.

20 Apr 2026

Circulating exosomal microRNAs offer a non-invasive biomarker for MASLD

Metabolic dysfunction-associated steatotic liver disease (MASLD) has become a global public health challenge with rapidly rising prevalence, especially in China. Despite advances in treatment, the underlying molecular mechanisms remain incompletely understood. A new research article published in the Chinese Medical Journal on March 16, 2026, provides critical insights into the role of exosomal microRNAs (miRNAs) in MASLD pathogenesis.

17 Apr 2026

Epigenetic changes allow cancer cells to shift identity and survive drugs

Cancer drugs are designed to shut tumors down. But sometimes, in the very act of attacking a tumor, treatment can also help a small fraction of cancer cells become harder to kill. A new study from researchers at the Institute for Systems Biology (ISB) shows that cancer cells may begin escaping therapy much earlier - as the therapy itself triggers a stress response that drives some cancer cells into a temporary drug-tolerant state.

16 Apr 2026

Microplastics lab studies may fail to reflect real-world exposure

Microplastics pose health risks, but lab studies often fail to reflect real-world exposure, highlighting critical gaps in toxicological research methodologies.

14 Apr 2026

Beetroot supplement raises nitric oxide markers in triathletes after one week

A randomized cross-over pilot study in 10 amateur male triathletes found that a beetroot-based multi-ingredient nitrate supplement increased nitric oxide-related and redox biomarkers over 7 days without evidence of lipid oxidative damage. The supplement was generally well tolerated, but the study did not measure whether these biochemical changes improved performance or recovery.

13 Apr 2026

Metformin protects neurons after brain injury by restoring mitochondrial health

TBI remains a major cause of death and long-term neurological disability worldwide, yet effective treatments for secondary injury are still lacking.

13 Apr 2026

Lab study shows cigarette smoke damaged lung cells more than e-cigarette vapor

Researchers found that cigarette smoke extract disrupted the lung cell barrier, increased IL-6 inflammation, and caused DNA damage in Calu-3 cells, while e-cigarette vapor extract showed no significant adverse effects on these measures under the study conditions. The authors caution that these were in vitro findings using liquid extracts and unflavored e-liquid, so they do not directly predict long-term human health outcomes.

12 Apr 2026

When omega-3 may help mental health and when they may not

Investigating omega-3 fatty acids, this review highlights their impact on mental health, inflammation, and the potential for therapeutic use in disorders.

10 Apr 2026

Microplastics found in human bile may be associated with gallstones

Findings show microplastics in bile may trigger cellular senescence, suggesting a link to gallstone disease and highlighting the need for further research.

9 Apr 2026

Study reveals lung-brain link between smoking and neurodegeneration

The correlation between smoking and neurodegeneration is well-documented, with one study from 2011 finding heavy smoking in midlife was associated with a greater than 100% increase in risk of dementia, Alzheimer's and vascular dementia more than two decades later.

8 Apr 2026

Why early-onset cancers are rising and how researchers plan to stop them

Early-onset cancers are rising worldwide, and this Cell Perspective argues that cancer prevention must move beyond static risk-factor snapshots toward life-course exposure mapping, tissue-level biology, and dynamic estimates of preventability. The authors propose three linked frameworks to speed discovery of cancer causes and translate those findings into more precise prevention and interception strategies.

8 Apr 2026

Antiviral drugs and shingles vaccines tied to lower dementia risk

New evidence links viral infections to dementia risk, suggesting vaccines and antiviral therapies may offer preventive pathways against cognitive decline.

8 Apr 2026

Childhood trauma inspires research into brain repair and recovery

What began as a child's encounter with trauma has grown into a research programme committed to understanding recovery.

7 Apr 2026

Can diet influence thyroid disease? A major review points to Mediterranean-style eating

This review found that thyroid health depends on more than iodine alone, with selenium, iron, zinc, vitamins, omega-3s, and overall eating patterns all shaping thyroid function and autoimmunity. It also concluded that Mediterranean-style diets are linked to more favorable thyroid outcomes, while unnecessary restrictive diets offer little benefit without a clear medical indication.

7 Apr 2026

Smoking shrinks key brain regions while cannabis shows weaker effects

The study highlights brain changes from tobacco use and calls for more research on cannabis, as its effects on brain structure remain inadequately understood.

7 Apr 2026

Challenging processed meat risks for dry-cured ham consumption

The effects of dry-cured ham on cardiometabolic health are nuanced, with evidence suggesting it may not adversely affect key health markers in moderation.

7 Apr 2026

New strategy exploits specific genetic vulnerability in colorectal cancer patients

Researchers have identified a novel therapeutic approach for colorectal cancer by exploiting a specific genetic vulnerability found in a majority of patients.

6 Apr 2026

Prickly pear may pack a surprising punch against metabolic syndrome

This narrative review examines how Opuntia ficus-indica fruit, or prickly pear, may help target multiple features of metabolic syndrome through its fiber, betalains, polyphenols, carotenoids, and other bioactive compounds. The authors conclude that the fruit shows promising mechanistic and preclinical potential, but stronger human trials are still needed before firm clinical claims can be made.

6 Apr 2026