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Adult-onset type 1 diabetes linked to higher cardiovascular and mortality risk

A new study in the European Heart Journal shows that people who develop type 1 diabetes in adulthood have an increased risk of cardiovascular disease and death, and that those diagnosed later in life do not have a better prognosis than those diagnosed earlier.

14 May 2025

Once-daily oral treatment shows positive results in first human study for obesity treatment

A first-in-human study of an investigational once-daily oral treatment for obesity (SYNT-101) demonstrated positive preliminary data for the safe and effective redirection of nutrient absorption into the lower intestine, the weight loss and metabolic management mechanism behind gastric bypass surgery.

14 May 2025

Trump’s fast-tracked deal for a copper mine heightens existential fight for Apache

Carrying eagle feathers and chanting prayers, Western Apache runners hit the road on a roughly 80-mile journey this month to try to save their sacred land from being fast-tracked by President Donald Trump into a copper mine.

14 May 2025

Obesity study highlights gap in perceptions between patients and physicians

A survey of adults living with obesity and their physicians across seven countries reveals a high disconnect between their perceptions about the causes of obesity and treatment goals.

13 May 2025

Lipid overload in ascites weakens immune response in ovarian cancer

A Ludwig Cancer Research study has identified a key mechanism by which advanced ovarian cancers suppress anti-tumor immune responses and resist immunotherapies.

13 May 2025

Fragmented care does not impact survival in rare sarcoma cases

Fragmented care - receiving medical treatment at more than one facility - has been associated with both positive and negative outcomes for cancer patients depending on a number of factors such as cancer type and treatment venue.

13 May 2025

DiffInvex identifies key genes driving chemotherapy resistance

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

13 May 2025

NIH grant supports Wayne State University research on protecting vision in people with diabetes

A four-year, $2.33 million grant from the National Eye Institute of the National Institutes of Health to Wayne State University is supporting research focused on improving and preserving vision and eye health in those with diabetes.

13 May 2025

Just a few plant-based swaps a week could make a difference to your heart

Replacing small weekly amounts of red or processed meat with plant-based foods was linked to modest reductions in cardiovascular disease risk in a large Finnish cohort study. The benefits varied by gender and food type, with the most consistent improvements seen when processed meat was replaced with vegetables.

13 May 2025

Hormone FGF21 reverses fatty liver disease by signaling the brain

A pioneering research study published today in Cell Metabolism details how the hormone FGF21 (fibroblast growth factor 21) can reverse the effects of fatty liver disease in mice. The hormone works primarily by signaling the brain to improve liver function.

13 May 2025

New AI approach helps detect silent atrial fibrillation in stroke victims

Detecting atrial fibrillation (AF) from brain scans using AI could support future stroke care, according to a recent study published in the Karger journal Cerebrovascular Diseases.

13 May 2025

BSO drug mimics anti-obesity effects of difficult sulfur amino acid restricted diet

A new research paper was published in Aging (Aging-US) Volume 17, Issue 4, on April 7, 2025, titled "Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet."

13 May 2025

Pentoxifylline offers no survival benefit for severe alcohol-associated hepatitis

Severe alcohol-associated hepatitis (sAH) remains a highly lethal condition with limited therapeutic options. Characterized by rapid liver decompensation, sAH is often accompanied by acute kidney injury (AKI), a complication that substantially worsens prognosis.

13 May 2025

New study identifies wedelolactone as a potent topical treatment for psoriasis

Announcing a new publication for Acta Materia Medica journal. Psoriasis is a chronic inflammatory disorder for which phosphodiesterase-4 (PDE4) inhibitors have emerged as promising therapeutic agents due to an ability to regulate inflammatory signaling pathways.

13 May 2025

Flavan-3-ols in tea and chocolate can lower blood pressure

We might have another reason to enjoy our daily cup of tea or small piece of dark chocolate, as a new study from the University of Surrey has found that naturally occurring compounds called flavan-3-ols - found in cocoa, tea, apples and grapes - may improve blood pressure and the health of our blood vessels.

13 May 2025

Researchers unlock new paths toward treating stress-related psychiatric disorders

In a comprehensive Genomic Psychiatry review article published today, researchers from the University of Rochester Medical Center have synthesized decades of research on stress hormone systems in primate brains, potentially unlocking new paths toward treating stress-related psychiatric disorders.

13 May 2025