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Tirzepatide outperforms semaglutide for weight loss in people without diabetes

A head-to-head trial found that tirzepatide led to significantly greater weight loss and waist reduction than semaglutide in adults with obesity but without diabetes. Over 72 weeks, tirzepatide helped more participants reach key weight loss milestones, with manageable side effects and strong metabolic benefits.

12 May 2025

Living near golf courses raises Parkinson’s disease risk, study finds

Living within 1 to 3 miles of a golf course is associated with a significantly higher risk of Parkinson’s disease, particularly in groundwater-vulnerable areas. The study suggests both drinking water contamination and airborne pesticides may contribute to elevated risk.

12 May 2025

Chokeberry juice reduces blood vessel resistance in people with pre-diabetes

A German crossover trial found that drinking polyphenol-rich red berry juice improved peripheral resistance and helped preserve muscle mass in pre-diabetic adults. No significant changes were seen in glucose control or oxidative stress over the 14-day interventions.

12 May 2025

Large language models help predict epileptogenic zones for surgery

Epilepsy, one of the most common neurological disorders characterized by recurrent seizures, affects over 70 million people worldwide.

12 May 2025

Novel Alzheimer's therapy shows low risk of severe side effects

The Food and Drug Administration's approval in 2023 of lecanemab - a novel Alzheimer's therapy shown in clinical trials to modestly slow disease progression - was met with enthusiasm by many in the field as it represented the first medication of its kind able to influence the disease.

12 May 2025

Hearing aids may help older adults combat social isolation

Providing hearing aids and advice on their use may preserve social connections that often wane as we age, a new study shows.

12 May 2025

Saving teeth through regeneration offers long-term benefits over implants

A major long-term study presented at EuroPerio11, the world's leading congress on gum health and implant dentistry by the European Federation of Periodontology (EFP), reveals that saving teeth with severe bone loss through periodontal regeneration (PR) offers benefits equal to - if not greater than - replacing them with dental implants or bridges.

12 May 2025

Vision loss heightens fall and mortality risks for seniors

Older adults with vision problems face a heightened risk of falls and premature death, according to a new University of Michigan study.

12 May 2025

High school athletes with ADHD face extended recovery from concussions

When athletes who have attention-deficit/hyperactivity disorder get concussions, their ADHD disorder may prolong recovery, researchers think.

12 May 2025

Study reveals low rate of opioid addiction medications after overdose

Medications proven to effectively treat opioid addiction are rarely given after emergency department visits for overdose, and who gets them varies, sometimes greatly, depending on race, ethnicity or geography, University of Michigan researchers say.

12 May 2025

Tirzepatide outperforms semaglutide in weight loss clinical trial

Tirzepatide (trade name Zepbound) promoted greater weight loss in individuals with obesity than did semaglutide (trade name Wegovy) in a clinical trial that compared the safety and efficacy of the injectable drugs.

12 May 2025

City of Hope opens largest outpatient facility to enhance cancer care

As advances in early detection and treatment transform cancer into a chronic disease, City of Hope, one of the largest and most advanced cancer research and treatment organizations in the U.S. with its National Medical Center named top 5 in the nation for cancer by U.S. News & World Report, opens its largest outpatient facility among its network of 38 U.S. locations.

12 May 2025

Breakthrough discovery offers hope for treating neurodegenerative diseases

Researchers have discovered how to block cells dying, in a finding that could lead to new treatments for neurodegenerative conditions like Parkinson's and Alzheimer's.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

GLP-1RAs show added protection against cancer beyond weight reduction

New research being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May) and published in the journal eClinicalMedicine finds that first generation weight-loss medications like liraglutide and exenatide appear to show anti-cancer benefits beyond weight loss.

11 May 2025

Scientists link specific gene variants to post-vaccine myocarditis and pericarditis

A genome-wide association study in Sweden identified rare genetic variants near the SCAF11 and LRRC4C genes that may be linked to heart inflammation following COVID-19 mRNA vaccination. The findings shed light on potential biological pathways driving vaccine-associated myocarditis and pericarditis, particularly among younger individuals.

11 May 2025

Vegetarians may need to watch thyroid health, especially with low iodine intake

Vegetarians had a modestly higher risk of developing hypothyroidism compared to high meat-eaters, but only after adjusting for BMI. No increased risk was seen for vegans or pescatarians in incident cases, though pescatarians showed a slight increase in baseline prevalence.

11 May 2025

Woman with rare genetic disorder delivers healthy baby after complex pregnancy

When Jessica Johnson, 36, began to experience labored breathing and heart palpitations, she quickly made an appointment to see a cardiologist.

11 May 2025

Time-restricted eating may be a promising strategy for sustaining long-term weight loss

Three months of time-restricted eating (TRE), irrespective of whether it is earlier or later in the day, may be a promising strategy for sustaining long-term weight loss in adults with overweight or obesity, according to preliminary results of a randomised controlled trial being presented at this year's European Congress on Obesity (ECO) in Malaga, Spain (11-14 May).

11 May 2025

New human ovaroid model offers insight into infertility and differences in sex development

A new model of tiny human ovary organoids, or ovaroids, has been developed from stem cells, according to research presented at the first Joint Congress between the European Society of Paediatric Endocrinology (ESPE) and the European Society of Endocrinology (ESE).

11 May 2025