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Red blood cells drive blood vessel damage in diabetes by exporting toxic vesicles

Red blood cell-derived extracellular vesicles in type 2 diabetes are actively taken up by the endothelium, transferring the enzyme arginase-1 and triggering oxidative stress. This mechanism helps explain vascular complications in diabetes and offers new targets for therapeutic intervention.

19 May 2025

Study reveals high rates of cannabis use disorder in older US veterans

A large national study of U.S. veterans aged 65–84 found that 10.3% reported cannabis use in the past 30 days, with over one-third of these meeting criteria for cannabis use disorder. Frequent use and inhaled forms of cannabis sharply increased the risk.

19 May 2025

Zebrafish study reveals hidden dangers of environmental toxins from tires

Emerging contaminants from rubber tires N-(1,3-Dimethylbutyl)-N'-phenyl-p-phenylenediamine (6PPD) and its oxidation product 6PPD-quinone (6PPDQ)-are raising new red flags for aquatic ecosystems.

19 May 2025

Experimental drug could offer pain relief without the side effects of opioids

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids.

19 May 2025

Study uncovers common trigger across gene mutations that cause ALS

Using the gene scissors CRISPR and stem cells, researchers at Stockholm University and the UK Dementia Research Institute (UK DRI) at King's College London have managed to identify a common denominator for different gene mutations that all cause the neurological disease ALS.

19 May 2025

Dementia patients in poorer areas of Quebec face unequal access to care

A new study has found stark differences in the dementia care received by people in richer and poorer neighborhoods in Quebec, despite the universal health-care system.

19 May 2025

Study explores impact of overlapping conditions on heart failure outcomes in older adults

Heart failure represents one of the most significant global health challenges, affecting millions worldwide and requiring subsequent hospitalization for many patients due to complications.

19 May 2025

Targeting cGAS shows promise for treating cardiac dysfunction after cardiac arrest

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Cardiac dysfunction is a prevalent and serious complication after cardiac arrest (CA), yet limited therapeutic interventions are available.

19 May 2025

Common anti-inflammatory drugs may aid virus spread

New research shows an unintended and unfortunate side effect of common drugs. They can simply help viruses spread.

19 May 2025

Sedentary behavior increases risk of death or cardiac events post-heart attack

People who sit or remain sedentary for more than 14 hours a day, on average, may have a higher risk of a cardiovascular event or death in the year after treatment at a hospital for symptoms of a heart attack such as chest pain, according to new research published today in the American Heart Association's peer-reviewed scientific journal Circulation: Cardiovascular Quality and Outcomes.

19 May 2025

Evolution of malaria protein family offers new drug targets

Researchers from the Francis Crick Institute and the Gulbenkian Institute for Molecular Medicine (GIMM) have shown that the evolution of a family of exported proteins in the malaria-causing parasite Plasmodium falciparum enabled it to infect humans.

19 May 2025

Karger Publishers releases free-access eBook "Healthy Aging"

Designed for doctors and health enthusiasts, "Healthy Aging" contains surprising scientific discoveries and practical guidance on nutrition, healthy sleep, maintaining a social network and physical fitness to contribute to longevity.

From S. Karger AG 19 May 2025

Repeated antibiotics in preterm infants linked to long-term lung problems

Repeated perinatal antibiotic exposure in very low-birth-weight preterm infants was associated with impaired lung function and a higher risk of asthma at early school age. The findings underscore the need for cautious antibiotic use and targeted respiratory health strategies in this high-risk group.

18 May 2025

Methotrexate found to be effective alternative to prednisone for pulmonary sarcoidosis

Prednisone is recommended as the first-line treatment for pulmonary sarcoidosis, but this steroid causes a number of unwanted side effects.

18 May 2025

Waist-to-height ratio emerges as strong predictor of heart failure risk

Waist-to-height ratio predicts heart failure incidence, according to research presented today at Heart Failure 2025, a scientific congress of the European Society of Cardiology (ESC).

18 May 2025

Many heart failure patients miss out on life saving specialist care

If you have cancer, you expect to see an oncologist, but if you have heart failure you may or may not see a cardiologist.

18 May 2025

Rising temperatures drive global surge in obstructive sleep apnea severity

Rising temperatures increase the severity of obstructive sleep apnea (OSA), according to a large new study published at the ATS 2025 International Conference.

18 May 2025

Skipping breakfast and losing sleep: Are US girls sacrificing health to slim down?

More than half of US adolescent girls want to lose weight, even those with a healthy BMI. Many pursue weight loss while adopting habits like skipping breakfast, poor sleep, and increased screen time, highlighting a need for better health interventions.

18 May 2025

Limited self sufficiency threatens global access to healthy and sustainable diets

Growing emphasis on self-reliance and trade barriers could impair the ability of people to consume healthy and sustainable diets around the world.

18 May 2025

City size reduces obesity and impulsivity through better lifestyle and education

Researchers analyzing data from 915 U.S. cities found that both obesity and impulsivity (measured by ADHD rates) are less common in larger cities, with physical inactivity linking ADHD to obesity. Education and mental healthcare access further influence these patterns, highlighting modifiable factors for urban health.

18 May 2025