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Exercise intervention reduces fall risk in elderly women on multiple medications

An exercise intervention aimed at elderly women was successful at reducing falls, especially among those with polypharmacy, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

11 Mar 2025

Self-sampling could reduce disparities in cervical screening

New research from University of Manchester experts suggests that introducing a UK-wide self-sampling program alongside existing ‘smear tests’ could help to remove most of the current barriers to cervical screening.

11 Mar 2025

Seafood consumption linked to prosocial behavior in children

Children who consumed the least amounts of seafood at 7-years-old were likely to be less 'prosocial' at ages 7 and 9 years than those who regularly consumed seafood, according to a new study.

11 Mar 2025

Integrated anti-aging strategy could reduce neurodegeneration

Aging significantly impacts neurodegeneration, increasing risks for diseases like Alzheimer's. Research focuses on therapies to enhance cognitive function.

11 Mar 2025

Switching from butter to plant-based oils linked to lower mortality risk

Researchers compare how the consumption of butter or plant-based oil impacts total and cause-specific mortality.

11 Mar 2025

Maternal cannabis use disorder linked to increased risk of child behavioral disorders

Researchers determine how maternal cannabis use disorder during and after pregnancy impacts the child’s behavior.

11 Mar 2025

Novel regulators in digestive tract disease progression and treatment

This new article published in Genes & Diseases highlights the critical role of tRNA-derived small RNAs (tsRNAs) in digestive tract diseases, positioning these molecules as potential biomarkers for diagnosis, prognosis, and targeted therapies. The comprehensive review explores the biogenesis, classification, and biological functions of tsRNAs, shedding light on their influence over cellular processes such as translation regulation, epigenetic modification, and protein interactions.

11 Mar 2025

Study reveals the role of transcription factors as therapeutic gateways in MAFLD

Metabolic dysfunction-associated fatty liver disease (MAFLD) has become a growing global health concern, affecting millions worldwide. This complex liver disorder ranges from simple steatosis to more severe forms, including metabolic dysfunction-associated steatohepatitis (MASH), which may progress to fibrosis, cirrhosis, and even liver cancer.

11 Mar 2025

Study investigates genetic mutations linked to occupational exposures

Occupational and environmental exposures can put specific groups of people at higher risk of cancer, including firefighters. A new study by investigators at Mass General Brigham examines a cancer rarely studied in firefighters: gliomas-a type of tumor that forms in the brain or spinal cord.

11 Mar 2025

Decoding programmed cell death in breast cancer

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC remains a significant global health challenge.

11 Mar 2025

Study highlights the role of ELF4 as a key transcription factor in development, immunity, and oncology

ELF4, a transcription factor belonging to the ETS family, has emerged as a pivotal regulator in cell differentiation, immune system function, and cancer progression. This newly published review underscores its molecular complexity and clinical significance, shedding light on its dual role in tumor suppression and oncogenesis.

11 Mar 2025

Deciphering the tumor-immune interplay in endometrial carcinoma

A new review article published in Genes & Diseases sheds light on the complex molecular mechanisms through which tumor-infiltrating immune cells regulate endometrial carcinoma (EC). As one of the most prevalent gynecological cancers, EC continues to challenge researchers and clinicians due to its dynamic interaction with the immune microenvironment.

11 Mar 2025

Study reveals TCM-Based strategies for ferroptosis modulation

Innovative insights into the role of ferroptosis, a unique form of programmed cell death, are reshaping the landscape of disease treatment. This growing field highlights how Traditional Chinese Medicine (TCM) can effectively modulate ferroptosis, offering novel therapeutic approaches for various conditions, including cancer, cardiovascular diseases, neurodegenerative disorders, and organ injuries.

11 Mar 2025

Harnessing lncRNAs for early diagnosis and intervention in acute kidney injury

A new review published in Genes & Diseases on long non-coding RNAs (lncRNAs) highlights their critical role in the development, diagnosis, and potential treatment of acute kidney injury (AKI) and chronic kidney disease (CKD). The findings emphasize the importance of exosomal lncRNAs, which function as molecular regulators in kidney pathology and hold promise for future biomarker discovery and therapeutic advancements.

11 Mar 2025

Global disparities in Alzheimer's and dementia burden linked to sociodemographic factors

An analysis of the global burden and temporal trends of Alzheimer's disease and other dementias (ADODs) reveals significant cross-country inequalities associated with a series of sociodemographic development-related risk factors, such as education, income, fertility, and health expenditure. The new study in the American Journal of Preventive Medicine, published by Elsevier, calls for the development of targeted prevention and control strategies in different countries.

11 Mar 2025

Ovarian cancer mutations across populations show similarities and unique differences

An extensive tumor genomic analysis of individuals with ovarian cancer, led by researchers from Huntsman Cancer Institute at the University of Utah (the U) and Emory University, revealed that Black women have nearly identical mutations to other previously studied populations.

10 Mar 2025

New test could predict life-threatening side effects of cancer immunotherapy

Medical researchers in Japan have discovered a way to predict a potentially life-threatening side effect of cancer immunotherapy before it occurs.

10 Mar 2025

One in three young people estimated to live with pediatric onset chronic conditions

The prevalence of chronic conditions has risen to unprecedented levels over the past twenty years, with nearly 1-in-3 young people estimated to now be living with pediatric onset conditions that significantly affect their lives, new research suggests.

10 Mar 2025

New study examines timing of prenatal stress on infant stress reactivity

A team of researchers at Michigan State University and the University of Michigan found new insights on the timing of prenatal stress and its effect on infant stress reactivity and temperament - including differences between genders.

10 Mar 2025

Can eating invasive species and forgotten crops boost Europe's food security?

European researchers propose diversifying diets with novel foods (NF), underutilized crops (NUS), and invasive species (IAS) to combat biodiversity loss and food insecurity, balancing ecological benefits with risks like regulatory barriers and consumer skepticism.

10 Mar 2025