A team from Hybridyne Imaging Technologies, Inc., and the U.S. Department of Energy's Brookhaven National Laboratory was among over 90 top technology innovators from across the nation and around the world competing in Arlington, Texas, March 16-17, for top honors at the WBT2010 showcase presented by Lockheed Martin.
Hybridyne's technology, called ProxiScan™, is capable of high-resolution imaging of prostate cancer. The unique component of the technology is a cadmium zinc telluride (CZT)-based compact gamma camera developed in collaboration with Brookhaven Lab scientists. The technology was presented to a sold-out WBT2010 audience of over 600 participants, including venture capital investors, federal agencies and licensees.
“The word is out that for investors, federal agencies and licensees seeking emerging technology opportunities, WBT offers the best deal flow in the nation,” said Paul Huleatt, WBT’s CEO. “We look forward to watching the progress of our WBT2010 presenters.”
According to Mr. Huleatt, approximately one-third of past WBT presenters have gone on to secure venture capital or a licensing/strategic partnership agreement. To date, past presenters have raised over $450 million in first (or next) round venture capital.
ProxiScan™: A Novel Camera for Imaging Prostate Cancer
Terry Lall, Hybridyne's President and CEO said, “One in six men in the U.S. will be diagnosed with prostate cancer in his lifetime, and one in 35 will die from the disease. Prostate cancer is the second leading cause of cancer deaths in men because there is no technology able to detect tumors at an early stage and localize them in fine detail, which can lead to early, life-saving treatment. ProxiScan™ can detect tumors almost 10 times smaller than conventional gamma cameras. It delivers high performance in a small package at a much lower cost than conventional nuclear medical instruments.”
The common way to diagnose prostate cancer is through a blood test that measures the levels of a protein produced by the prostate gland called prostate-specific antigen, or PSA. Elevated PSA levels can indicate prostate cancer as well as some benign conditions, so often men must have an invasive biopsy to test for cancer.
Other methods for confirming a diagnosis of prostate cancer include either ultrasound imaging or conventional nuclear medical imaging techniques. These current imaging approaches have limitations, however. Benign and cancerous tumors cannot easily be distinguished by ultrasound, and fibrous tissues can be mistakenly identified as tumors if patients have had radiation treatment of the prostate previously. Traditional nuclear-imaging systems, such as positron emission spectroscopy and single photon emission computed tomography, produce lower-resolution images and are less efficient than Hybridyne’s compact digital camera. Also, the detectors in these systems are too large to be used for endoscopic measurements.
In contrast, Hybridyne's new CZT-based gamma camera is small enough for trans-rectal prostate cancer diagnosis, after the patient is injected with a tracer radiopharmaceutical. The high-resolution CZT detector, coupled with its miniaturized readout electronics, is the cutting-edge technology that drives the novel imaging system. Using this new technology, the working distance between the gamma camera and the prostate gland is minimized, allowing urologists to obtain better images with a smaller amount of injected radioactive tracer, compared to conventional nuclear medical systems.
“ProxiScan's™ cost, portability and performance will make it a must-have tool at all medical facilities focused on prostate-cancer diagnosis and treatment," Lall said.
Hybridyne continues to collaborate with Brookhaven Lab to develop 3-D hand-held imaging devices to investigate other cancers (breast, colorectal, ovarian, and cervical) and heart disease, and to integrate its ProxiScan™ camera with other imaging modalities, such as ultrasound.
ABOUT Hybridyne Imaging Technologies, Inc.
The company’s focus is on the development of compact gamma cameras for imaging radiopharmaceuticals distributed in the body. The approach uses solid-state detectors and miniaturized digital circuits for creating new diagnostic tools and treatment capabilities. Visit Hybridyne’s web site.