Review confirms that cranberry products help prevent urinary tract infections

NewsGuard 100/100 Score

Drinking cranberry juice has long been a mythical prevention strategy for women who develop a urinary tract infection – and new medical evidence shows consuming cranberry products is an effective way to prevent a UTI before it gets started.

A global study looking at the benefits of cranberry products published in Cochrane Reviews has determined cranberry juice and its supplements reduce the risk of repeat symptomatic UTIs in women by more than a quarter, in children by more than half, and in people susceptible to UTI following medical interventions by about 53%. 

Review: Cranberries for preventing urinary tract infections. Image Credit: Irina Green 27 / ShutterstockReview: Cranberries for preventing urinary tract infections. Image Credit: Irina Green 27 / Shutterstock

Cranberry juice and healthcare supplements commonly including the fruit, such as capsules and tablets, have long been promoted as a readily available solution to ward off infection. Still, the most recent review in 2012, with evidence from 24 trials, showed no benefit from the products.

The medical scientists behind this updated review from Flinders University and The Children's Hospital at Westmead aimed to update these findings as an important step in determining the effectiveness of cranberry products by looking at 50 more recent trials that included almost 9000 participants.

"This incredible result didn't really surprise us, as we're taught that when there's more and better evidence, the truth will ultimately come out. UTIs are horrible and very common; about a third of women will experience one, as will many elderly people and also people with bladder issues from spinal cord injury or other conditions," says the study lead author Dr. Gabrielle Williams.

"Even back in 1973, my mum was told to try cranberry juice to prevent her horrible and frequent UTIs, and for her it's been a saviour. Despite me niggling in her ear about evidence, she's continued to take it daily, first as the nasty sour juice and in recent years, the easy to swallow capsules. As soon as she stops, wham the symptoms are back. As usual, it turns out that mum was right! Cranberry products can help some women prevent UTIs."

Flinders University epidemiologist Dr. Jacqueline Stephens, a study co-author, says if the UTI persists untreated, it can move to the kidneys and cause pain and more complications, including sepsis in severe cases, so prevention is the most effective way to reduce risks.

"Most UTIs are effectively, and pretty quickly, treated with antibiotics, sometimes as little as one dose can cure the problem. Unfortunately, in some people UTIs keep coming back. Without being sure if or how it works, some healthcare providers began suggesting it to their patients. It was a harmless, easy option at the time. Even centuries ago, Native Americans reportedly ate cranberries for bladder problems, leading somewhat more recently, to laboratory scientists exploring what it was in cranberries that helped and how it might work."

"The studies we looked at included a range of methods to determine the benefits of cranberry products. The vast majority compared cranberry products with a placebo or no treatment for UTI and determined drinking cranberries as a juice or taking capsules reduced the number of UTIs in women with recurrent cases, in children and in people susceptible to UTi's following medical interventions such as bladder radiotherapy."

"It's also important to consider that few people reported any side effects with the most common being tummy pain based on the results. We also did not find enough information to determine if cranberry products are more or less effective compared with antibiotics or probiotics in preventing further UTIs."

The data also shows no benefit for older adults, pregnant women, or people with bladder emptying problems. 

Senior Author Professor Jonathan Craig, Vice President and Executive Dean of the College of Medicine & Public Health at Flinders University, says the real benefits of cranberry products became apparent when the researchers expanded the scope of the review to include the most recently available clinical data.

"This is a review of the totality of the evidence and as new evidence emerges, new findings might occur. In this case, the new evidence shows a very positive finding that cranberry juice can prevent UTI in susceptible people," says Professor Craig.

"We have shown the efficacy of cranberry products for the treatment of UTIs using all the evidence published on this topic since the mid-nineties. The earlier versions of this review didn't have enough evidence to determine efficacy and subsequent clinical trials showed varied results, but in this updated review the volume of data has shown this new finding."

The study authors conclude that while cranberry products do help prevent UTIs in women with frequent recurrence, more studies are needed to clarify further who with UTI would benefit most from cranberry products.

Source:
Journal reference:

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment
Post

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.

You might also like...
Hospital sinks fuel antibiotic-resistant bacteria spread