The electronic cigarette and vaping industries are expanding. In these products, the mixtures which are typically used are called e-juices, e-liquids, or e-fluids. In order to guarantee these e-liquids' qualities, it is necessary to test the most important quality parameters. Nicotine content in e-liquids constitutes one important quality control parameter.
Liquid or gas chromatography usually determines the level of nicotine in tobacco. A significantly more affordable alternative for this determination is non-aqueous acid base titration.
It is possible to apply the aqueous acid base titration put forward in this article to the determination of nicotine. This is because e-liquids do not contain other components which may interfere with the titration.
This technique constitutes a reliable and affordable method of determining e-liquids' nicotine content, as well as their nicotine starting material. This can ensure these products' quality.
Nicotine starting material for e-liquids
No sample preparation is required
|804 Ti stand
|802 Rod stirrer
|Dosing unit 10 mL
||c(HCl) = 0.1 mol/L
If possible, this solution should be bought from a supplier.
Dependent upon the expected content of nicotine, a sample weighing between 3-20 g is weighed into clean 120 ml disposable beakers, into which roughly 35 ml of ultrapure water is added. This solution gets stirred for 2 minutes before being titrated with c(HCl)= 0.1 mol/L until after the equivalence point.
|Min. waiting time
|Max. waiting time
|Meas. point density
|Sample (n = 3)
||Nicotine content /
|Nicotine starting material
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