Digital Pathology News and Research

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Spatial modeling of tissue compartments predicts breast cancer treatment response

HER2-positive breast cancer accounts for about 20% of breast cancer cases and is generally associated with more aggressive behavior and a higher risk of distant metastasis, while pathologic complete response (pCR) after neoadjuvant chemotherapy is strongly linked to better survival outcomes.

20 May 2026

Multimodal AI improves prediction of PIK3CA mutations in breast cancer

Breast cancer is one of the most common malignancies worldwide, and mutations in the PI3K/AKT/mTOR (PAM) signaling pathway are prevalent in its development.

21 Apr 2026

AI model predicts immunotherapy response in lung cancer patients

A biology-guided artificial intelligence model applied to routine pathology slides accurately predicted outcomes and response to immunotherapy in patients with metastatic non-small cell lung cancer (NSCLC), according to a study presented at the American Association for Cancer Research (AACR) Annual Meeting 2026, held April 17-22.

20 Apr 2026

Leadership in digital pathology with launch of next-generation Aperio GT Elite scanner and Aperio iQC software

Leica Biosystems' Aperio GT Elite scanner and iQC software streamline digital pathology workflows, ensuring high-quality results and operational efficiency.

From Leica Biosystems 24 Mar 2026

Distinct spatial tumor–immune ecosystems predict lung cancer treatment response

Researchers at Moffitt Cancer Center have identified distinct spatial tumor–immune ecosystems that predict whether patients with advanced non–small cell lung cancer will benefit from immunotherapy.

5 Mar 2026

Leica Biosystems revolutionizes histology workflows with global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System

Leica Biosystems, a Danaher company and a global leader in anatomic pathology solutions, is redefining histology workflows with the global launch of the Leica CM1950 Cryostat with DualEcoTec Cooling System.

From Leica Biosystems 12 Feb 2026

Digital pathology and the PathoVerse: A conversation with Dr. Singh

Learn how digital connectivity and the PathoVerse are improving pathology workflows and accelerating access to expert diagnostics.

From PathPresenter 12 Dec 2025

Engineered virus therapy triggers powerful immune responses in glioblastoma

A new study led by Break Through Cancer's Accelerating Glioblastoma (GBM) Therapies Through Serial Biopsies TeamLab has revealed that an engineered virus therapy, CAN-3110, triggered powerful immune responses deep inside glioblastoma tumors that were invisible to standard imaging like MRI, according to early analyses of two patients with recurrent GBM.

9 Oct 2025

Repeated sampling offers insight into glioblastoma therapy response

A multi-institutional study from the Accelerating GBM Therapies Through Serial Biopsies TeamLab, led by investigators from the Mass General Brigham Cancer Institute, found that serially testing tumor samples can help detect when a cancer treatment is activating the immune system in recurrent glioblastoma (GBM), even when traditional imaging measures cannot.

8 Oct 2025

PathPresenter announces general availability of remote second opinion web portal on Amazon Web Services

PathPresenter, a leading Image Management System and workflow platform for digital pathology, is pleased to announce general availability of ConsultConnect, its innovative solution for digital pathology consultations and remote second opinions, powered by Amazon Web Services (AWS).

3 Oct 2025

Ligolab and Pathpresenter announce strategic partnership to deliver seamless digital pathology workflows

LigoLab, a leading provider of enterprise laboratory information system (LIS) software and fully integrated laboratory revenue cycle management (lab RCM) solutions, and PathPresenter, a global leader in digital pathology image viewing and management solutions, today announced a strategic partnership.

From PathPresenter 27 Sep 2025

Contact sports tied to hidden brain damage independent of CTE

This fall, tens of millions of people will be at risk for chronic traumatic encephalopathy (CTE), a degenerative brain disease caused by repeated head impacts from contact sports like football, soccer, and ice hockey, or military service.

17 Sep 2025

EVIDENT to Acquire Pramana, Inc.

Evident announces a definitive agreement to acquire Pramana, Inc., a leading manufacturer of digital pathology solutions.

13 Aug 2025

Pathpresenter receives FDA 510(K) clearance for digital pathology clinical viewer

PathPresenter, a leading Image Management System and workflow platform for digital pathology, has received U.S. Food and Drug Administration (FDA) 510(k) clearance for the PathPresenter Clinical Viewer for the purpose of primary diagnosis.

25 Jun 2025

Precision medicine approach improves treatment for soft tissue sarcomas

A study conducted by researchers from the Agency for Science, Technology and Research (A*STAR), National Cancer Centre Singapore (NCCS) and National University of Singapore (NUS), in collaboration with biotech company, KYAN Technologies, has demonstrated that a precision medicine approach improves treatment selection for patients with soft tissue sarcomas (STS) in a clinical setting.

7 May 2025

AI tools improve detection of key immune structures in melanoma

Researchers from the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) have applied AI-driven processes for detecting tertiary lymphoid structures (TLS) in thousands of digital images of melanoma tumor tissue, significantly enhancing TLS identification and survival predictions for operable stage III/IV patients.

24 Apr 2025

Source Bioscience acquires Cambridge Clinical Laboratories

Source BioScience UK Ltd, an industry-leading provider of genomic services and histopathology diagnostics, today announced it had completed the acquisition of Cambridge Clinical Laboratories (CCL), a leading Cambridge-based provider of clinical, personalized healthcare testing services.

10 Apr 2025