Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Camelid IFNs could play important role in combating emerging zoonotic pathogens

In a recent study published in the Developmental & Comparative Immunology journal, the discovery of a novel form of mammalian interferon-Beta (IFN-β) with four cysteine residues from the dromedary camel and the five remaining members of the mammalian suborder Tylopoda is described.

17 May 2022

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

In a recent study published in the journal Vaccines, researchers developed plant-based monoclonal antibodies (mAbs) against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

17 May 2022

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Researchers from Ain Shams University have been exploring the use of compounds isolated from Aspergillus sp. against SARS-CoV-2.

13 May 2022

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Cells have certain proteins that help them adhere to each other while covering body surfaces and organs. Loss of these identifying proteins could result in cellular progression towards cancer and, subsequently, metastasis.

9 May 2022

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

A recent report published in the STAR Protocols journal depicted a protocol for an antibody-based proximity labeling to discover biotinylated interactors of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

3 May 2022

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers examined the efficiency of the main protease (Mpro) inhibitor against SARS-CoV-2.

29 Apr 2022

Researchers investigate O-glycosylation in cells infected with Ebola

Researchers from the Copenhagen Center for Glycomics have been investigating O-glycosylation in cells infected with Ebola virus in order to better understand the disease.

28 Apr 2022

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

In a study published in Cells, researchers have been investigating the effects of this extract for use against COVID-19.

27 Apr 2022

Metrohm USA celebrates 10th annual young chemist award winner

Metrohm USA is pleased to announce the winner of its 2022 Young Chemist Award, Colby Ott. Colby is a Ph.D. candidate at West Virginia University's Forensic and Investigative Science Department in Morgantown, West Virginia, where his research centers around developing novel methods for screening seized drugs.

From Metrohm USA Inc. 20 Apr 2022

Study investigates the production of a virosome-based COVID-19 vaccine candidate

In a new study, different signal peptides, baculovirus transfer vectors, cell lines, infection techniques, and formulation buffers were investigated with the purpose of building a scalable bioprocess to generate high-quality S protein for incorporation in a virosome-based COVID-19 vaccine candidate.

18 Apr 2022

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

In a recent study, researchers assessed the anti-COVID-19 efficacy of Salvia miltiorrhiza Bunge.

14 Apr 2022

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

researchers discussed and identified the systemic functions and interactions of 52 active cell surface receptor tyrosine kinases, providing insights on RTK-RTK interactions and substrates, RTK-protein complexes, and signaling pathways.

13 Apr 2022

COVID-19 could change the levels of proteins related to male reproductive function

Many people who recover from COVID-19 experience long-term symptoms, such as brain fog or heart problems. Increasing evidence suggests that the virus can also impair fertility.

7 Apr 2022

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Researchers characterized SARS-CoV-2 spike (S) isolates extracted from the samples of two individuals infected with the virus in Peru (ΔN25) and Brazil (ΔN135) in January 2021.

6 Apr 2022

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Researchers investigated the effectiveness of a circRNA vaccine against SARS-CoV-2 and its Delta and Omicron variants, which elicited significant antibody and T-cell responses in mice and rhesus macaques.

6 Apr 2022

Gut bacterium may be an important factor in resistance to antihypertensive medications

Almost half of the U.S. adult population has high blood pressure - or hypertension - and about 20% of these patients have treatment-resistant hypertension.

5 Apr 2022

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

A new study discovered immunoglobulins with powerful broad-acting neutralizing capacity against SARS-CoV-2 from SARS-CoV-2 convalescents.

5 Apr 2022

Researchers use breast milk to identify new set of protein biomarkers for cancer

A simple blood test for women of all ages and risk levels could one day be possible thanks to a new set of protein biomarkers that researchers identified using breast milk.

4 Apr 2022

Soy molasses and kudzu roots may help fight against pediatric tumors

Soy molasses and kudzu roots contain isoflavonoids with high antioxidant and cytotoxic activity, scientists have discovered.

30 Mar 2022

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

A recent study presented topologically engineered fragment crystallizable-fusion proteins and antibodies as therapeutic options for diseases like human coronaviruses infections and cancers.

25 Mar 2022

Chromatography News and Research

Further Reading

Camelid IFNs could play important role in combating emerging zoonotic pathogens

Neutralization of SARS-CoV-2 by plant-made neutralizing monoclonal antibodies

Researchers identify compounds from Aspergillus that may be effective against SARS-CoV-2

Scientists identify the role of phospholipid in maintaining epithelial cellular adhesion

Proximity labeling to identify high-confidence SARS-CoV-2 interactors

Study reports an orally available SARS-CoV-2 Mpro inhibitor with potent in vivo antiviral activity

Researchers investigate O-glycosylation in cells infected with Ebola

The preclinical potential of a herb used in traditional Chinese medicine for the treatment of COVID-19

Metrohm USA celebrates 10th annual young chemist award winner

Study investigates the production of a virosome-based COVID-19 vaccine candidate

The preclinical potential of S. miltiorrhiza extracts for the treatment of COVID-19

The molecular context and substrate profiles of human cell surface receptor tyrosine kinases

COVID-19 could change the levels of proteins related to male reproductive function

Study highlights immune escape mutations in viral N-terminal domain supersite of SARS-CoV-2 spike variants

Study shows circular RNA vaccine provides robust protection against SARS-CoV-2 in mice and rhesus macaques

Gut bacterium may be an important factor in resistance to antihypertensive medications

Investigating extensive SARS-CoV-2 neutralizing immunoglobulins from COVID-19 recovered subjects

Researchers use breast milk to identify new set of protein biomarkers for cancer

Soy molasses and kudzu roots may help fight against pediatric tumors

Topologically designed antibody candidates for SARS-CoV-2 and cancer therapies

Enhancing confidence in chemical ionization spectrometry data eBook

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