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Breakthrough gene discovery offers new hope for medulloblastoma therapy

Scientists at The Hospital for Sick Children (SickKids) have identified a key gene that could lead to next-generation treatments for medulloblastoma, the most common malignant brain tumor in children.

24 Jan 2025

Low-dose initiation of buprenorphine for people using fentanyl fails to deliver expected results

During the COVID-19 pandemic, when fentanyl overdoses surged, doctors were desperate to find ways of helping their patients.

24 Jan 2025

Study reveals lifespan gap between educated and uneducated Americans

Across more than 3,000 US counties, vast geographic differences with a widening gap were registered between the least and most educated, with a longer lifespan for those with a higher level of education.

24 Jan 2025

Review highlights the role of mitochondrial Ca2+ imbalance in neurodegenerative diseases

Mitochondria are crucial organelles for cellular homeostasis, regulating processes such as ATP production, reactive oxygen species (ROS) management and Ca2+ signaling.

24 Jan 2025

Medicaid insurance, socioeconomic disadvantage linked to poorer survival after heart transplant

A new study led by UCLA Health highlights the link between socioeconomic disadvantage, Medicaid insurance, and poorer survival rates after heart transplantation.

24 Jan 2025

Key immune cells required for tissue repair following liver injury

Our livers contain many different types of immune cells. New research by the team of Prof. Charlotte Scott (VIB-UGent Center for Inflammation Research) and colleagues now reveals that a specific activation state of one of these cell types is required for tissue repair following injury.

24 Jan 2025

Dapagliflozin plus calorie restriction boosts remission rates in adults with type 2 diabetes and obesity

Findings indicate that dapagliflozin and calorie restriction together improve weight loss and metabolic health, increasing the likelihood of diabetes remission.

24 Jan 2025

Researchers elucidate the significance of birth in neural stem cell maintenance

A research group led by Kazunobu Sawamoto, a professor at Nagoya City University and National Institute for Physiological Sciences, and Koya Kawase, a pediatric doctor at Nagoya City University Hospital, has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).

24 Jan 2025

Study links circulating short-chain fatty acids to type 2 diabetes risk

Short-chain fatty acids (SCFAs) serve as key signaling molecules linking gut microbiota and host health. Microbially produced SCFAs in the colon are generally acknowledged for their beneficial effects on cardiometabolic health, including enhancing insulin secretion, reducing plasma cholesterol and glucose levels, and controlling energy intake through the modulation of enteroendocrine hormones.

24 Jan 2025

Positive mental well-being can help maintain a physically active lifestyle

According to a recent study, the tendency to experience positive affectivity contributed to people being physically active or even increasing their activity during the COVID-19 restrictions.

24 Jan 2025

Research develops framework to compare lab, AI, and simulation data

The successful and safe delivery of therapeutics relies on understanding how easily drugs can pass through biological barriers which protect cells.

24 Jan 2025

Study offers new insight into how nature and nurture shape aggression in males

Like humans, mice will compete over territory and mates, and show increased confidence in their fighting skills the more they win.

24 Jan 2025

HPV16 vaccine shows promise in treating precancerous cervical lesions

A therapeutic vaccine targeting human papillomavirus type 16 (HPV16) induced regression in high-grade precancerous cervical lesions, according to the results from a phase II clinical trial published in Clinical Cancer Research, a journal of the American Association for Cancer Research.

24 Jan 2025

Healthy habits take longer to form than expected

We're nearly one month into 2025, but if you're struggling to hold onto your New Year's resolution, stay strong, as University of South Australia research shows that forming a healthy habit can take longer than you expect.

24 Jan 2025

Breakthrough study targets tumor cell clusters to prevent metastasis

Certain tumor types do not remain at their point of origin but spread throughout the body and form metastases.

24 Jan 2025

Volunteering reduces loneliness in older adults

Researchers examine how social volunteering affects the social and emotional aspects of loneliness among older adults in China.

24 Jan 2025

Study reveals sex-specific differences in microglial response to CSF1R inhibition

Researchers investigate the sex-dependent microglial response to a colony-stimulating factor 1 receptor (CSF1R) inhibitor.

24 Jan 2025

Decades of DNA expansion linked to Huntington’s disease neurodegeneration

Researchers uncover how slow CAG repeat expansions in neurons drive Huntington’s disease over decades.

24 Jan 2025

Study finds successful treatment of childhood obesity lowers long-term health risks

Effective treatment of childhood obesity significantly lowers long-term health risks, including type 2 diabetes and hypertension, promoting better adult health.

24 Jan 2025

Revvity ignites scientific breakthroughs at SLAS2025

Revvity, Inc. is set to unveil its groundbreaking new Phenologic.AI™ software at SLAS2025 in San Diego, January 27-29. Designed to redefine cellular imaging workflows for Revvity’s Harmony™ and Signals Image Artist™ software packages, the Phenologic.AI software leverages pre-trained deep-learning models to analyze brightfield images, providing an additional multiplexing channel and streamlined workflows for live cell analysis.

From Revvity 24 Jan 2025