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Parental divorce in childhood tied to 61% higher stroke risk in older adults

Experiencing parental divorce in childhood is associated with a significantly higher risk of stroke in older adulthood, even after accounting for key risk factors such as income, depression, and diabetes.

23 Jan 2025

Crick researchers identify key Y chromosome genes influencing sperm development

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice.

23 Jan 2025

Boosting BCL6 may counteract muscle loss from GLP-1 medications

About one in eight adults in the United States has tried or currently uses a GLP-1 medication, and a quarter of those users cite weight loss as their main goal.

23 Jan 2025

New approach to treating ependymoma with leukemia drug

Rakesh Jain PhD, Director of the E.L. Steele Laboratories for Tumor Biology at Massachusetts General Hospital and A. Werk Cook Professor of Radiation Oncology at Harvard Medical School, is senior author of a new study in PNAS, Targeting EPHB2/ABL1 Restores Anti-Tumor Immunity in Preclinical Models of Ependymoma.

23 Jan 2025

Research shows sharp growth in sedative and anxiety medication use disorders in youth

The prevalence of diagnosed disorders from recurrent use of sedative, hypnotic and antianxiety medications in adolescents and young adults has increased sharply since 2001, according to Rutgers Health researchers.

23 Jan 2025

Microplastics in the bloodstream may pose hidden risks to brain health

Trapped immune cells laden with microplastics starve the brain of oxygen—mouse study links vascular blockages to memory loss and motor deficits, with lingering risks even after symptoms fade.

23 Jan 2025

Two-thirds of people with post-COVID-19 syndrome experience long-term effects

Two-thirds of people with post-COVID-19 syndrome have persistent, objective symptoms – including reduced physical exercise capacity and reduced cognitive test performances – for a year or more, with no major changes in symptom clusters during the second year of their illness, according to a new study published January 23rd in the open-access journal PLOS Medicine by Winfried Kern of Freiburg University, Germany, and colleagues.

23 Jan 2025

Study reveals post-pandemic rise in child deaths

While child deaths in England fell temporarily during the COVID-19 pandemic, they have now risen to new heights, a new study from researchers at the University of Bristol and based on unique National Child Mortality Database (NCMD) data has found.

23 Jan 2025

Non-industrialized diet improves health and reduces disease risk

Researchers have found that a newly developed diet inspired by the eating habits of non-industrialised societies can significantly reduce the risk of a number of chronic diseases – and are to share recipes with the public.

23 Jan 2025

Pomalidomide shows promise in enhancing immune responses in myeloma

A new editorial was published in Oncoscience's Volume 12 on January 14, 2025, titled "Pomalidomide improved immune profiles in myeloma."

23 Jan 2025

Study reveals abelacimab’s potential to improve anticoagulation safety for AFib patients

Abelacimab, a factor XI inhibitor, demonstrated a 62–69% reduction in major bleeding compared to rivaroxaban in atrial fibrillation patients at moderate-to-high stroke risk, with comparable safety and efficacy. While ischemic stroke rates were slightly higher, they were not statistically significant, warranting further phase 3 trials for confirmation.

23 Jan 2025

Researchers map genetic differences across children with Wilms tumor

Genetically tailored treatment plans for children with a type of kidney cancer could help provide the most effective care while minimizing side effects as much as possible.

23 Jan 2025

Metronomic chemotherapy offers hope for children with neuroblastoma

Neuroblastoma is the most common extracranial solid tumor in children, with nearly 50% of cases diagnosed at an advanced stage, often with metastatic disease.

23 Jan 2025

Empa researchers improve epidemic forecasts with reproduction matrix

The reproduction number R is often used as an indicator to predict how quickly an infectious disease will spread.

23 Jan 2025

Study links chemesthetic sensitivity to food preferences and consumption

Oral chemesthesis, or chemically induced tactile sensation in the mouth area, affects the consumption and recalled pleasantness of certain foods and drinks, such as chilli sauce and alcoholic beverages.

23 Jan 2025

New genomic insights could transform bipolar disorder treatment

Study published in Nature identifies nearly 300 genomic regions associated with bipolar disorder, and 36 key genes involved in the disease.

23 Jan 2025

What causes behavioral side effects in popular weight loss drugs?

The study of GLP1R variants shows associations with cardiometabolic traits and behavioral changes, highlighting indirect effects of GLP1RA on mental health.

23 Jan 2025

Researchers investigate a new combination therapy against cancer

A research team at the Medical University of Vienna led by Maria Sibilia has investigated a new combination therapy against cancer.

23 Jan 2025

Prehabilitation associated with fewer complications and improved recovery after surgery

Actively preparing for major surgery by exercising and improving diet (known as "prehabilitation") is associated with fewer complications, less time in hospital, and improved recovery and quality of life in adults, finds an analysis of clinical trials published by The BMJ today.

23 Jan 2025

Adults with ADHD found to have reduced life expectancy

Adults who have been diagnosed with attention deficit hyperactivity disorder (ADHD) may be living shorter lives than they should, finds a world-first study led by UCL researchers.

23 Jan 2025