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Genetic mutation linked to schizophrenia in both humans and mice

A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with the same mutation, a rare finding of a direct genetic link to psychosis, report researchers at the University of Illinois Urbana-Champaign and colleagues in Massachusetts and Germany.

19 Feb 2025

Ginger's furanodienone compound may offer new treatment for inflammatory bowel disease

An international team led by researchers at the University of Toronto has found a compound in ginger, called furanodienone (FDN), that selectively binds to and regulates a nuclear receptor involved in inflammatory bowel disease (IBD).

19 Feb 2025

F446L mutation in Lassa virus offers clues for new therapeutic approaches

Announcing a new article publication for Zoonoses journal. Lassa virus (LASV) glycoprotein complex (GPC) contains retained stable-signal peptide (SSP), glycoprotein 1 (GP1), and glycoprotein 2 (GP2).

19 Feb 2025

Hydrodissection may offer hope for post-amputation pain relief

A reliable method to treat post-amputation pain remains elusive, but a new Northwestern Medicine study conducted in collaboration with Ukrainian physicians suggests that hydrodissection - a simple procedure that injects fluid around nerves - may reduce residual limb pain and opioid dependence.

19 Feb 2025

Study uncovers molecular mechanisms behind insulin resistance in skeletal muscle

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide.

19 Feb 2025

Regulatory crackdown on online prescriptions of weight-loss drugs

Online pharmacies must now conduct in-person consultations before dispensing weight-loss medications, ensuring safe and appropriate use of high-risk drugs.

19 Feb 2025

Lifestyle and environmental factors play bigger role in health and premature death than genetics

A new study led by researchers from Oxford Population Health has shown that a range of environmental factors, including lifestyle (smoking and physical activity), and living conditions, have a greater impact on health and premature death than our genes.

19 Feb 2025

New mRNA technique targets disease cells while sparing healthy ones

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

19 Feb 2025

Neuroestrogens likely contribute to appetite regulation

Although a woman's ovaries produce the most estrogen, various types of estrogen are also synthesized throughout different tissues in the body, including the brain's neurons.

19 Feb 2025

New method uses stool DNA to track diet and health

Scientists have developed a breakthrough method to track diet using stool metagenomic data.

19 Feb 2025

More screen time, more stress? Study links device use to teen mental health

Research shows that excessive screen time contributes to stress and depression in adolescents, highlighting the need for balanced digital habits and exercise.

19 Feb 2025

Common antidepressant Fluoxetine protects from sepsis-induced death

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19 Feb 2025

Plant immune responses may offer insights into human brain diseases

A groundbreaking study led by a team of researchers at the University of Kentucky's Martin-Gatton College of Agriculture, Food and Environment has revealed a surprising biochemical connection between plant immune responses and human neurological health.

19 Feb 2025

Lasting impact of long COVID and the protective benefits of vaccination

Researchers explore the mental and physical health outcomes in patients with long COVID.

19 Feb 2025

Direct connection found between memory and sensory processing centers in brain

A newly identified part of a brain circuit mixes sensory information, memories, and emotions to tell whether things are familiar or new—and important or just "background noise."

19 Feb 2025

Recreational exercise, not work activity, linked to lower type 2 diabetes risk

Researchers have found that engaging in moderate to vigorous physical activity during leisure time, regardless of occupational physical activity, is associated with a reduced risk of type 2 diabetes. A combination of sedentary leisure-time activity and demanding occupational activity may increase the risk.

19 Feb 2025

Understanding disparities in same-day breast cancer diagnostics

Despite similar availability of diagnostic technologies to women of different racial and ethnic groups, significant disparities were seen in who actually received same-day diagnostic services and biopsies after abnormal mammogram findings, new research shows.

19 Feb 2025

New study reveals LRP1's crucial role in bone formation and joint development

Skeletal conditions such as developmental dysplasia of the hip (DDH), osteoporosis, and osteoarthritis affect millions worldwide, often causing chronic pain and disability. These disorders stem from complex genetic and environmental interactions that disrupt bone formation and joint development.

19 Feb 2025

Nerinetide shows promise in stroke treatment meta-analysis

The Calgary Stroke Program, a joint University of Calgary and Alberta Health Services initiative at Foothills Medical Centre, has been involved with three papers published this week in The Lancet and Lancet Neurology-the ESCAPE-NEXT trial, the FRONTIER trial, and an individual patient-level meta-analysis across three trials.

19 Feb 2025

Drinking more water may lower heart disease risk, but too much coffee and tea could raise it

Drinking water may help reduce cardiovascular disease (CVD) risk, while excessive coffee and tea intake (≥6 cups/day) increases the likelihood of CVD, with stronger effects in women.

19 Feb 2025