In a Journal of Orthopedic Research study, scientists used 3D printing to repair bone in the joints of mini-pigs, an advance that may help to treat osteoarthritis in humans.
Specifically, the investigators used 3D printing with a needle-array to generate articular cartilage and subchondral bone using constructs composed of mesenchymal stem cells derived from fat tissue. Printed constructs were implanted into osteochondral defects created in the knees of six mini-pigs. Computed tomography and magnetic resonance imaging tests revealed significant repair within the defects at three and six months post-implantation.
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