Winter babies at 'higher risk of mental health disorders'

NewsGuard 100/100 Score

New research suggests that babies born autumn and winter are at increased risk of developing mental health disorders, as mothers giving birth during these seasons have higher levels of the stress-related hormone, cortisol.  

The study, which is the first to report results on the effects of the seasons on maternal salivary cortisol levels in late pregnancy, investigated the links between seasonality and the risk of children developing anxiety or depression in later life.

Fetus in the wombGagliardiPhotography | Shutterstock

Using data from the longitudinal Grown in Wales (GiW) cohort, the study, which was published in Psychoneuroendocrinology, included 316 Caucasian women living in South Wales who provided saliva samples and filled out the Edinburgh Postnatal Depression Scale (EPDS) and the trait subscale of the State-Trait Anxiety Inventory (STAI).

The study begins by explaining the Developmental Origins of Health and Disease (DOHaD) suggests “adverse environmental exposures during critical periods of intrauterine development lead to changes in the fetus that persist after birth impacting the individual’s genetically determined health trajectory.

These changes increase the risk of developing diseases later in life such as type 2 diabetes, hypertension, heart disease and psychiatric disorders.”

The seasons can also trigger conditions such as seasonal affective disorder (SAD), which is a type of depression that often worsens during winter, although some people can experience deeper feelings of depression during summer.

However, the link between the seasons and maternal mood and the subsequent outcomes for children is “relatively unexplored”, as stated by the study.

Although the researchers found no link between the season during which babies were born and the level of depression of anxiety the mothers displayed, links were found between the seasons and maternal levels of salivary cortisol.

Seasonal changes affect mental health risk

Cortisol is a steroid hormone produced by the adrenal glands, and is often termed a “stress hormone”. Pregnancy, along with alcoholism and depression among other environmental and health conditions can increase the amount of cortisol in the saliva.

“Our data shows that autumn and winter babies are exposed to particularly high levels just before they are born,” Professor Rosalind John, an author of the study, explained.

Figures included in the study show that the highest levels of salivary cortisol were found in the autumn and winter months, with cortisol levels dropping by 0.05μg/dL and 0.06μg/dL in the spring and summer months respectively.

On average, women giving birth in the autumn or winter had 20 percent more salivary cortisol just before delivery than those giving birth in spring or summer. As high levels of cortisol in pregnant women have previously been associated with a higher risk of children developing mental health disorders, the new findings could explain why these disorders are more common in people born during the winter months.”

Professor Rosalind John, Senior Author

Professor John added the results do not explain “the reason why women who give birth in winter or autumn have these higher levels of cortisol.”

These results are in direct contrast to a previous study carried out in 2015 that reported cortisol levels (measured with hair samples instead of saliva samples) were highest in the summer and autumn and lowest in the winter. It is important to note that cortisol levels in the hair can be influenced by other factors that do not affect salivary concentrations of cortisol.

The authors claim that despite this discrepancy between study results, this new research remains important, as “salivary cortisol is sensitive to the seasonal changes that occur in the UK” and that the associations they have found between the seasons and risk of depression and anxiety “may offer an explanation for research demonstrating that season of birth influences the risk of developing other conditions later in life.”

The research team draw on evidence showing that schizophrenia is diagnosed more often in people who are born in January and February, as a result of being exposed to high levels of cortisol in utero, in part due to the winter season.

The study concludes,

Our finding that maternal salivary cortisol levels at term were lowest in spring and summer and highest in autumn and winter will certainly have implications for the interpretation of studies that do not take into account seasonality when using salivary cortisol as a biomarker in pregnancy.”

Limitations of the current study

The cohort size, at just over 300 women, is small, and is a key limitation to highlight. Another limitation is that the study only focuses on women who were recruited for the research before a pre-surgical elective cesarean section (ELCS) appointment, and results may not extend to women giving birth via alternative methods.

Additionally, non-Caucasian women were not included in the study to “minimize the confounder of ethnicity which can impact cortisol” and as such, results cannot be extended to women of different ethnicities.

Journal reference:

Garay, S. M., et al. (2019). Seasonal variation in salivary cortisol but not symptoms of depression and trait anxiety in pregnant women undergoing an elective caesarean section. Psychoneuroendocrinology.

Lois Zoppi

Written by

Lois Zoppi

Lois is a freelance copywriter based in the UK. She graduated from the University of Sussex with a BA in Media Practice, having specialized in screenwriting. She maintains a focus on anxiety disorders and depression and aims to explore other areas of mental health including dissociative disorders such as maladaptive daydreaming.


Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Zoppi, Lois. (2019, August 05). Winter babies at 'higher risk of mental health disorders'. News-Medical. Retrieved on April 23, 2024 from

  • MLA

    Zoppi, Lois. "Winter babies at 'higher risk of mental health disorders'". News-Medical. 23 April 2024. <>.

  • Chicago

    Zoppi, Lois. "Winter babies at 'higher risk of mental health disorders'". News-Medical. (accessed April 23, 2024).

  • Harvard

    Zoppi, Lois. 2019. Winter babies at 'higher risk of mental health disorders'. News-Medical, viewed 23 April 2024,


The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News Medical.
Post a new comment

While we only use edited and approved content for Azthena answers, it may on occasions provide incorrect responses. Please confirm any data provided with the related suppliers or authors. We do not provide medical advice, if you search for medical information you must always consult a medical professional before acting on any information provided.

Your questions, but not your email details will be shared with OpenAI and retained for 30 days in accordance with their privacy principles.

Please do not ask questions that use sensitive or confidential information.

Read the full Terms & Conditions.