Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Study shows strong protective effect of IgG3 antibodies in SARS-CoV-2 infection

Researchers published a study on the expression and functional analyses of a neutralizing mAb with identical variable domains but different constant HCs, representing IgG1-4.

6 Oct 2021

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Many children, as well as adults, dislike Brassica vegetables, such as broccoli, cauliflower, cabbage and Brussels sprouts.

22 Sep 2021

Preventing Wine Adulteration

Gordon Burns is the technical director and co-founder of ETS Laboratories, which runs specialist wine analysis labs based in the Napa Valley in California. The North American wine industry has quite a different story to tell than honey that was discussed in another interview when it comes to authenticity issues.

From Bruker BioSpin Division 22 Sep 2021

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

In a recent study, RBD produced in various cell types are characterized in-depth, comparing their applicability for future COVID-19 research.

21 Sep 2021

German chancellor delighted after company visit to KNAUER, calling the company a pearl

German Chancellor Dr. Angela Merkel visited Berlin-based manufacturer of high-tech laboratory instruments KNAUER Wissenschaftliche Geräte GmbH on Friday, Sept. 10, 2021.

From KNAUER Wissenschaftliche Geräte GmbH 16 Sep 2021

Drug accumulation alters gut bacterial metabolism and composition

In a research paper recently published in the journal Nature by Klünemann et al. (September 8th, 2021), the interaction of 15 diverse drugs with 25 common strains of gut bacteria is investigated, revealing 70 bacteria-drug interactions that include 29 entirely novel mechanisms not yet reported.

15 Sep 2021

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

A recent report published in the journal Cell Discovery has described the immunogenicity and protective efficacy of a novel coronavirus disease 2019 (COVID-19) subunit vaccine candidate. The vaccine induces robust immune responses in rodents and non-human primates and protects the animals against severe disease.

12 Sep 2021

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

A COVID-19 vaccine, created from a virus-like nanoparticle that displays SARS-CoV-2 spike protein RBDs, effectively protects animal model from infection.

10 Sep 2021

The role of nanobodies in capturing and containing SARS-CoV-2

Scientists have repurposed the Nb Ty1 for the detection and neutralization of SARS-CoV-2.

8 Sep 2021

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

A team of investigators, led by Dr. Benjamin F. Mann, from Merck, USA have published a new study on the preprint server bioRxiv*. They have used a biochemical approach to control the glycosylation profile of the S protein receptor-binding domain (RBD) and to analyze the effect of different glycosylation patterns on receptor binding.

30 Aug 2021

Migraine-inducing peptides may protect against diabetes by influencing insulin production

People who get migraines are less likely to develop type 2 diabetes, while some people who develop diabetes become less prone to migraines.

26 Aug 2021

Efficient, Low Maintenance Evaporator

Porvair Sciences announces that its Ultravap® Mistral XT 150 blowdown evaporator is now able to operate at temperatures up to 80°C thereby significantly increasing the rate of evaporation of both organic solvents and aqueous solutions.

From Porvair Sciences Limited 26 Aug 2021

Researchers identify a cluster of small molecules that contribute to coffee's mouthfeel

Coffee drinkers intuitively recognize the pleasure of swallowing a smooth, rich brew versus a watery one.

24 Aug 2021

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Three independent studies in the Journal of Pharmaceutical Analysis explore the potential uses and applications of quantitative analytical tools in the characterization and quality assessment of biological and medicinal compounds.

19 Aug 2021

Scientists identify a potent neutralizing nanobody against SARS-CoV-1

In a recently published article in the journal Virologica Sinica, scientists have described the development and validation of a potent nanobody that targets the receptor-binding domain (RBD) of severe acute respiratory syndrome coronavirus (SARS-CoV). The nanobody efficiently and specifically blocks the interaction between RBD and angiotensin-converting enzyme 2 (ACE2) and neutralizes the virus.

19 Aug 2021

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

A new study describes the structure of a crucial enzyme present in SARS-CoV-2.

8 Aug 2021

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

A team of international scientists has recently developed virus-like particles (VLPs) by coating liposomes with the synthetic spike glycoprotein of SARS-CoV-2.

28 Jul 2021

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

In this interview, Mickaël Watiez, Head of Research & Development at Lesieur, and Dagmar Behmer, Marketing Manager Applied Spectroscopy at Bruker Optics talk to News-Medical Life Sciences about the role FT-NIR Spectroscopy can play in testing edible oils and fats.

From Bruker Optics 28 Jul 2021

KNAUER donates 15,000 Euros for the victims of Germany’s flood disaster

The manufacturer of high-tech laboratory instruments, KNAUER Wissenschaftliche Geräte GmbH, has committed to helping the victims of the West Germany’s recent flooding disaster with a donation of €15,000.

From KNAUER Wissenschaftliche Geräte GmbH 27 Jul 2021

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Scientists from the UK have recently identified an antiviral metabolite 3'-Deoxy-3',4'-didehydro-cytidine as a potential serum biomarker to diagnose active severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the medRxiv* preprint server while awaiting peer review.

27 Jul 2021

Chromatography News and Research

Further Reading

Study shows strong protective effect of IgG3 antibodies in SARS-CoV-2 infection

In-mouth production of volatile sulfur compounds causes children to dislike Brassica vegetables

Preventing Wine Adulteration

Comparison of recombinant SARS-CoV-2 receptor binding domain produced in mammalian, insect, and bacterial cells

German chancellor delighted after company visit to KNAUER, calling the company a pearl

Drug accumulation alters gut bacterial metabolism and composition

Scientists develop a novel and potent SARS-CoV-2 RBD-homodimer vaccine

Virus-like nanoparticle vaccine effective against SARS-CoV-2 in animal model

The role of nanobodies in capturing and containing SARS-CoV-2

Role of glycans on the SARS-CoV-2 spike protein in human receptor interaction

Migraine-inducing peptides may protect against diabetes by influencing insulin production

Efficient, Low Maintenance Evaporator

Researchers identify a cluster of small molecules that contribute to coffee's mouthfeel

Studies shed light on the versatility, precision, and sensitivity of quantitative analytical tools

Scientists identify a potent neutralizing nanobody against SARS-CoV-1

New study describes SARS-CoV-2 ExoN enzyme that promotes antiviral resistance

Spike-containing virus-like particles induce robust sterilizing immunity against SARS-CoV-2 in macaques

The Role of FT-NIR Spectroscopy in Edible Oils and Fats

KNAUER donates 15,000 Euros for the victims of Germany’s flood disaster

Scientists identify an antiviral metabolite as a potential serum biomarker for SARS-CoV-2 infection

Enhancing confidence in chemical ionization spectrometry data eBook

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Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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