Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Muscle-derived vesicles heal damaged cells and reverse disease in new study

Researchers discovered that mitochondria-rich extracellular vesicles (Ti-mitoEVs) from skeletal muscle can deliver healthy mitochondria to damaged cells, restoring energy and promoting tissue repair in mice. The approach reversed acute muscle injury and chronic kidney disease, offering a promising new regenerative therapy.

21 Jul 2025

The Proteoform Puzzle: Unlocking the Next Frontier

In the interview, Lloyd M. Smith discusses proteoforms, an area of research worthy of the next Human Genome Project.

From Pittcon 10 Jul 2025

Warming temperatures and CO2 levels threaten food quality

New preliminary research suggests that a combination of higher atmospheric CO2 and hotter temperatures contribute to a reduction in nutritional quality in food crops, with serious implications for human health and wellbeing.

9 Jul 2025

Early exposure to plastics raises young children’s asthma risk

A large international study found that early-life exposure to phthalates, common chemicals in plastics, is modestly associated with increased risks of asthma, wheeze, and rhinitis in children under five. No consistent associations were found for bisphenols, and effects were generally small.

6 Jul 2025

Fidelio Capital partners with Alphalyse to accelerate the global roll-out of LC-MS host cell protein analytics

Alphalyse, a fast-growing Danish specialist contract research organization (CRO) that has developed GMP‑validated liquid‑chromatography mass‑spectrometry (LC‑MS) assays for host‑cell‑protein (HCP) impurity testing in biologic drugs, today announces that Fidelio Capital has acquired a majority stake in the company.

From Alphalyse A/S 2 Jul 2025

New screening method for Parkinson's analyzes odors in ear wax

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis.

18 Jun 2025

COVID-19 triggers metabolic signatures in kids that mirror adult heart risk

Children with acute COVID-19 and MIS-C show significant disruptions in lipid metabolism, including patterns resembling adult severe COVID-19. These findings highlight potential long-term cardiovascular risks in pediatric SARS-CoV-2 cases and underscore the need for follow-up care.

16 Jun 2025

Skin biomarkers may offer noninvasive diagnosis for pediatric eosinophilic esophagitis

A groundbreaking study led by National Jewish Health researchers suggests that the skin may serve as a potential biomarker for a chronic allergic disease of the esophagus called eosinophilic esophagitis (EoE) in children.

6 Jun 2025

Waters introduces BioResolve Protein A Affinity Columns to accelerate antibody titer measurement, enhancing process agility and batch quality

Waters Corporation today announced the launch of the BioResolve™ Protein A Affinity Columns with MaxPeak™ Premier Technology, providing precise titer measurements.

From Waters Corporation 2 Jun 2025

Study sheds light on the link between gut microbiota, isoflavones, and geniposide hepatotoxicity

A recent study published in Engineering has shed light on the relationship between gut microbiota, isoflavones, and geniposide hepatotoxicity.

26 May 2025

Black tea kombucha reduces harmful gut microbes linked to obesity

Regular consumption of black tea kombucha for eight weeks beneficially shifted gut microbiota composition in both normal-weight and obese adults.

14 May 2025

How urine caffeine levels may help detect diabetic eye damage early

Researchers found that higher urinary levels of caffeine and specific metabolites, especially in men, were significantly associated with diabetic retinopathy risk. The cross-sectional study used NHANES 2009–2014 data and highlights potential biomarkers for early detection in diabetic populations.

7 May 2025

Waters integrates Multi-Angle Light Scattering Detectors with empower software for improved biologics quality control and simplified regulatory compliance

Waters Corporation today announced that its Empower™ Software now supports biologics data acquisition and quality control (QC) analysis from Multi-Angle Light Scattering (MALS) and differential Refractive Index (RI) instruments in its Wyatt Technology™ Portfolio.

From Waters Corporation 7 May 2025

Tomato and fruit juice improve quality of life for kids with asthma

Study suggests these antioxidant-rich juices may be a well-tolerated, practical addition to standard childhood asthma management.

6 May 2025

Advancing benzodiazepine detection for toxicology

Learn how experts are advancing benzodiazepine analysis and detection using insights from the lab.

From Waters Advanced Diagnostics 5 May 2025

Leveraging the Radian ASAP in standard casework

Explore how the Radian ASAP mass spectrometer is being used to streamline and enhance seized drug screening.

From Waters Advanced Diagnostics 30 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Obesity changes how the gut responds to plant compounds, researchers report

Researchers found that the impact of polyphenols rutin and genistein on the human fecal metabolome varies significantly by body mass index (BMI). Lower BMI individuals showed more diverse metabolic responses, revealing how gut health and obesity could shape polyphenol metabolism.

28 Apr 2025

Carotid artery plaque contains elevated micronanoplastics

People with plaque in the blood vessels of their neck have a higher amount of tiny plastic particles in those vessels compared to people with healthy arteries.

22 Apr 2025

Plastic additives found in 85% of foods raise concern for infant health

Researchers assessed plasticizer levels in foods typical of the Spanish diet and found widespread contamination, with infants showing the highest exposure. Certain additives, like DEHP, exceeded safety thresholds in high-exposure scenarios.

21 Apr 2025