Alzheimer's & Dementia News and Research

Latest Alzheimer's & Dementia News and Research

Short sleep and high blood pressure may increase brain damage

People with high blood pressure who also lack sleep may be at increased risk of reduced cognitive performance and greater brain injury, Monash University research has found.

2 Dec 2024

UK’s hearing loss organizations address misleading claims about dementia

The UK’s leading hearing loss organizations have joined forces to highlight misleading reports by some health professionals and the media that hearing loss causes dementia, and treating hearing loss will reduce our individual risk of dementia.

2 Dec 2024

Understanding the role of sleep in dementia and associated illnesses

A new review was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21, titled, "Sleep deprivation in dementia comorbidities: focus on cardiovascular disease, diabetes, anxiety/depression and thyroid disorders."

2 Dec 2024

Study highlights the critical role of TLR7 in sex-biased Alzheimer’s-related demyelination

Inhibiting an immune signaling protein called TLR7 may help preserve the protective layer surrounding nerve fibers in the brain during both Alzheimer's disease and ordinary aging, suggests a study led by researchers at Weill Cornell Medicine.

2 Dec 2024

Visceral fat found to contribute to Alzheimer's disease development

Researchers have linked a specific type of body fat to the abnormal proteins in the brain that are hallmarks of Alzheimer's disease up to 20 years before the earliest symptoms of dementia appear, according to a study being presented today at the annual meeting of the Radiological Society of North America (RSNA).

2 Dec 2024

Homebound seniors living alone often slip through health system’s cracks

Carolyn Dickens, 76, was sitting at her dining room table, struggling to catch her breath as her physician looked on with concern.

2 Dec 2024

Men face sharper brain aging from obesity and heart risks

Obesity and cardiovascular risk factors accelerate brain volume loss, with males experiencing earlier and more significant impacts, highlighting the importance of early interventions to prevent neurodegeneration.

1 Dec 2024

Flaws in study design may limit detection of cognitive effects in diet trials

Researchers review the role of diet in preventing cognitive decline and dementia.

28 Nov 2024

Study links combined risk factors for aggressive behavior in men with CTE

People who have chronic traumatic encephalopathy (CTE) who have a family history of mental illness may have a higher risk of aggression in middle age, according to a study published in the November 27, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology.

27 Nov 2024

TRiC mutations found to cause developmental brain malformations in children

In 1992, Judith Frydman, PhD, discovered a molecular complex with an essential purpose in all of our cells: folding proteins correctly.

27 Nov 2024

Research shows "Alzheimer's in a dish" model can accelerate drug discovery

A decade ago, researchers introduced a new model for studying Alzheimer's disease. Known as "Alzheimer's in a dish," the model uses cultures of mature brain cells suspended in a gel to recapitulate what takes place in the human brain over 10 to 13 years in just six weeks.

27 Nov 2024

Study unveils key mechanism in Alzheimer's disease

A new study from the University of Liverpool represents a significant step forward in scientists' understanding of Alzheimer's disease.

27 Nov 2024

Cardiovascular disease risk linked to early brain decline in men

Men with cardiovascular disease risk factors, including obesity, face brain health decline a decade earlier - from their mid 50s to mid 70s - than similarly affected women who are most susceptible from their mid 60s to mid 70s, suggest the findings of a long term study, published online in the Journal of Neurology Neurosurgery & Psychiatry.

26 Nov 2024

Machine learning tool detects early signs of Alzheimer's in mice

Subtle signs of Alzheimer's disease can emerge decades before a diagnosis - often in the form of irregular behaviors that reflect very early stages of brain dysfunction.

26 Nov 2024

Researchers explore the impact of primary progressive aphasia on quality of life

Imagine gradually losing the ability to express yourself - not because you've forgotten the words, but because they simply won't come out.

26 Nov 2024

Nasal spray shows promise in combating Alzheimer's

A future treatment for Alzheimer disease may involve a nasal spray. Researchers at Università Cattolica and Fondazione Policlinico Universitario A. Gemelli IRCCS have discovered that by inhibiting the brain enzyme S-acyltransferase (zDHHC) through a nasal-spray drug, they can counteract the cognitive decline and brain damage typical of the disease.

26 Nov 2024

Hormone therapy in early menopause proves safe but lacks cognitive benefits

Early menopausal hormone therapy neither benefits nor harms long-term cognition, offering reassurance but no protection against cognitive decline in healthy women.

26 Nov 2024

Addressing the challenges of cognitive impairment detection in primary care

Early detection of cognitive impairment is essential for improving patient outcomes, but primary care settings face significant challenges in screening. This special report summarizes key points and gaps in knowledge about methods for detecting cognitive impairment in primary care clinics.

25 Nov 2024

Brain volume loss linked to Alzheimer's treatment may be caused by amyloid plaque removal

A loss of brain volume associated with new immunotherapies for Alzheimer's disease may be caused by the removal of amyloid plaques, rather than the loss of neurons or brain tissue, finds a study led by UCL researchers.

25 Nov 2024