Using benchtop NMR for tobramycin identification in compendial testing

Nuclear Magnetic Resonance (NMR) spectroscopy is specified by the European Pharmacopoeia as the primary identification method for the aminoglycoside antibiotic tobramycin. This study demonstrates the straightforward application of that procedure using the benchtop Fourier 80 NMR spectrometer.

It also addresses limitations of the current method and explores strategies to improve its robustness and reliability, leveraging the capabilities of the Fourier 80. With its compact, cryogen-free design, the Fourier 80 is well-suited for integration into routine Quality Control (QC) laboratories.

As a modern analytical instrument, the Fourier 80 not only supports compendial compliance for tests like tobramycin identification but also provides the adaptability needed to align with evolving regulatory expectations for both qualitative and quantitative analysis.

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About Bruker BioSpin - NMR, EPR and Imaging - Pharma

Welcome to Bruker BioSpin and the world's most comprehensive range of NMR and EPR spectroscopy and preclinical imaging research tools. The Bruker BioSpin Group of companies develop, manufacture and supply technology to research establishments, commercial enterprises and multi-national corporations across countless industries and fields of expertise.

Bruker BioSpin is continuing to revolutionize the design, manufacture and distribution of life science, preclinical, process control and analytical research tools based on magnetic resonance and multimodal imaging technologies. Bruker BioSpin is the worldwide technology and market leader in magnetic resonance technologies (NMR, EPR) and offers the largest portfolio of imaging modalities for preclinical and industrial research under a single brand.


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Last updated: Oct 8, 2025 at 11:17 AM

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