Chromatography News and Research

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Chromatography in Greek means to ‘write with colors.’ It is a versatile separation technique developed in 1903 by Mikhail Tswett, a Russian botanist. He separated colorful plant pigments using a column of calcium carbonate. Ever since its discovery, chromatography has evolved as a powerful tool in the lab for the separation and identification of different compounds in a mixture.

Core sugars in breast milk fuel gut and brain health beyond 12 months

Researchers reviewed 13 studies of human milk oligosaccharides (HMOs) through 24 months of breastfeeding, analyzing 4,786 samples. Six “core” HMOs remained dominant, with total concentrations plateauing after 12 months and evidence suggesting persistence into the second year.

8 Sep 2025

Roasted Arabica coffee hides powerful antidiabetic molecules

Three novel coffee diterpene esters, caffaldehydes A, B, and C, were discovered in Arabica beans, showcasing significant alpha-glucosidase inhibitory activity.

3 Sep 2025

Compounds show significant inhibitory effects on α-glucosidase

Three of the compounds demonstrated significant inhibitory effects on α-glucosidase, a key enzyme in carbohydrate digestion. The findings could pave the way for new functional food ingredients targeting type 2 diabetes.

2 Sep 2025

Exploring testosterone's influence on cardiovascular, metabolic, reproductive, and mental health

For decades, testosterone has been recognized as the primary driver of male reproductive development and secondary sex characteristics.

1 Sep 2025

Glycosylation emerges as a key player in kidney disease progression

Kidney diseases affect nearly 700 million people worldwide and are a growing cause of mortality and health care costs.

29 Aug 2025

Mediterranean diet lowers dementia risk by altering key metabolites

Researchers linked genetics, plasma metabolites, and Mediterranean diet adherence to dementia risk in two large US cohorts, showing APOE4 homozygotes had distinct metabolic pathways. Diet-related metabolites mediated protection, highlighting precision-prevention opportunities.

26 Aug 2025

Synthetic Psychedelics: A Growing Public Health Concern

In this interview, Jonathan Ferguson discusses how knowledge of an emerging public health concern identified at Pittcon 2024 has evolved a year on.

From Pittcon 26 Aug 2025

New method enables comprehensive analysis of metabolites in biological samples

Researchers from the McCullagh Group in Oxford University's Department of Chemistry have published an innovative method in Nature Protocols today (22 August) that provides comprehensive analysis of metabolites found in cells, tissues and biofluids.

22 Aug 2025

Fish oil supplementation can reduce risk of developing type 2 diabetes in prediabetic individuals

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality.

20 Aug 2025

New strategies to tackle resistant foodborne pathogens

Innovative approaches in food and beverage analysis are transforming pathogen detection and control, emphasizing the role of natural compounds and sequencing.

19 Aug 2025

Study shows promising anti-diabetic potential of coffee's functional components

18 Aug 2025

Researchers develop precise tool to identify omega positions in lipids

Omega-3 fatty acids are known to be an essential part of a healthy diet. As humans cannot produce them, they have to be consumed in sufficient amounts. However, omega-6, -7, -9, and -10 fatty acids also play important roles in the metabolism of fats.

11 Aug 2025

Flavonols found in foods can block drug resistance protein and boost medication absorption

Researchers identified specific flavonols that potently inhibit breast cancer resistance protein (BCRP), a key driver of drug resistance and poor oral drug absorption. The study found that these flavonols can reverse chemotherapy resistance in vitro and boost drug exposure in animal models, though clinical translation remains uncertain.

6 Aug 2025

Breast milk fatty acids help babies sleep longer, study finds

Researchers found that higher levels of polyunsaturated fatty acids (PUFAs) in human milk are associated with longer sleep duration in exclusively breastfed two-month-old infants. The strongest effects were observed for daytime (diurnal) sleep, especially with omega-3 and omega-6 fatty acids.

5 Aug 2025

Tailored granola transforms gut bacteria and improves mood

A study reveals that custom granola can boost gut health and mood by increasing beneficial bacteria and short-chain fatty acids based on individual microbiota.

4 Aug 2025

New research reveals why fiber-rich diets fuel you better than refined foods

This study quantifies how much energy the human body harvests from gut microbial fermentation of dietary fiber, integrating bacterial physiology, diet, and metagenomic data. Results reveal that dietary fiber, not microbiome composition, mainly determines the amount of short-chain fatty acids absorbed, impacting daily energy and metabolic health.

31 Jul 2025

Powerful bioactives found in overlooked Amazonian fruits

Lesser-known Amazonian fruits exhibit strong antioxidant and antimicrobial properties, highlighting their role in public health and biotechnology research.

31 Jul 2025

Prenatal phthalates lower boys' verbal IQ but lift girls' performance IQ, Canadian study reveals

Prenatal exposure to certain phthalates, especially DiDP, was linked to slightly lower IQ scores in preschoolers, with boys appearing more vulnerable. Other phthalates, like MMP and MBzP, showed small positive associations, but mixture effects were not significant.

29 Jul 2025

Female body odor variations can shape male behavior and emotions

Researchers at the University of Tokyo explored how female body odor can influence behaviors in men. They found certain scent compounds in female body odor increased during ovulation and can subtly influence how men feel.

28 Jul 2025

Blocking a single gene disrupts vitamin D metabolism and cancer pathways in new cell study

Researchers identified SDR42E1 as a key regulator of vitamin D absorption and sterol metabolism in colorectal cancer cells. Disruption of this enzyme altered cancer-related pathways and cell viability, highlighting its potential as a therapeutic target.

21 Jul 2025