Sandalwood mimicking odorant could stimulate hair growth in humans

A chemical that mimics sandalwood has been found to have the ability to stimulate hair growth among humans finds a new study. This brings hope for people losing hair worldwide.

Researchers from Monasterium Laboratory, Münster, have expressed hope that this new chemical could treat hair loss effectively and are trying the drug for its effectiveness on human volunteers. Professor Ralf Paus, a scientist at the University of Manchester who led the research called this an “amazing finding.” He said that this widely used odorant that is used cosmetically in multitude of products has been seen for the first time to remodel a “normal human mini-organ [a hair].” The team found that there was a chemical pathway in the hair follicles that was affected by this chemical. This promoted hair growth and also slowed the death of the follicles. The results of the study appeared in the latest issue of the journal Nature Communications.

The chemical in question is called Sandalore. The chemical is used to make perfumes and soaps to recreate the smell of sandalwood. The team noted that this odorant chemical stimulates special cells within the nose. The team found that not just cells within the nasal passages these chemicals also stimulates other cells in the body such as hair follicles.

Red sandal wood. Image Credit: Rifad / Shutterstock
Red sandal wood. Image Credit: Rifad / Shutterstock

They noted that there is a receptor called OR2AT4 that can be stimulated by Sandalore. This receptor was found in the outer layers of the hair follicles. They explain that the hair follicle receptors are capable of “smelling” the chemical using their special receptors. When applied over the outer scalp tissues, Sandalore could decrease hair fall or follicular death as well as stimulate new hair growth. The results were clinically significant say the researchers.

This study was sponsored by a company in Italy - Giuliani Pharma S.p.A., that provides Sandalore in a cosmetic product to stimulate hair said Paus. Scalp tissues were taken for this study from patients undergoing a face lift surgery. The tissues were exposed either to Sandalore or to rose-like odour Phenirat. Phenirat is known to be a OR2AT4 blocker. Within 6 days hair growth was seen in the tissues exposed to Sandalore. Paus explained that this was followed by a “very small, short and preliminary clinical pilot study” with just 20 female volunteers who were given Sandalore to be applied over their scalp. Larger clinical trials are expected to start next year said Paus.

Source: https://www.nature.com/articles/s41467-018-05973-0

Dr. Ananya Mandal

Written by

Dr. Ananya Mandal

Dr. Ananya Mandal is a doctor by profession, lecturer by vocation and a medical writer by passion. She specialized in Clinical Pharmacology after her bachelor's (MBBS). For her, health communication is not just writing complicated reviews for professionals but making medical knowledge understandable and available to the general public as well.

Citations

Please use one of the following formats to cite this article in your essay, paper or report:

  • APA

    Mandal, Ananya. (2018, September 18). Sandalwood mimicking odorant could stimulate hair growth in humans. News-Medical. Retrieved on July 16, 2019 from https://www.news-medical.net/news/20180918/Sandalwood-mimicking-odorant-could-stimulate-hair-growth-in-humans.aspx.

  • MLA

    Mandal, Ananya. "Sandalwood mimicking odorant could stimulate hair growth in humans". News-Medical. 16 July 2019. <https://www.news-medical.net/news/20180918/Sandalwood-mimicking-odorant-could-stimulate-hair-growth-in-humans.aspx>.

  • Chicago

    Mandal, Ananya. "Sandalwood mimicking odorant could stimulate hair growth in humans". News-Medical. https://www.news-medical.net/news/20180918/Sandalwood-mimicking-odorant-could-stimulate-hair-growth-in-humans.aspx. (accessed July 16, 2019).

  • Harvard

    Mandal, Ananya. 2018. Sandalwood mimicking odorant could stimulate hair growth in humans. News-Medical, viewed 16 July 2019, https://www.news-medical.net/news/20180918/Sandalwood-mimicking-odorant-could-stimulate-hair-growth-in-humans.aspx.

Comments

The opinions expressed here are the views of the writer and do not necessarily reflect the views and opinions of News-Medical.Net.
Post a new comment
Post
You might also like... ×
Complement system shown to remove dead cells in retinitis pigmentosa, contradicting previous research